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Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development.

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Title: Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development.
Authors: Miller CN; Diabetes Center, University of California, San Francisco, San Francisco, CA, USA.; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Proekt I; Diabetes Center, University of California, San Francisco, San Francisco, CA, USA.; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., von Moltke J; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA.; Department of Immunology, University of Washington, Seattle, WA, USA., Wells KL; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Rajpurkar AR; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Wang H; Center for Immunology, Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA., Rattay K; Division of Developmental Immunology, Tumor Immunology Program, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Division of Immunology, Harvard Medical School, Boston, MA, USA., Khan IS; Diabetes Center, University of California, San Francisco, San Francisco, CA, USA.; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA., Metzger TC; Diabetes Center, University of California, San Francisco, San Francisco, CA, USA.; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; Bristol-Myers Squibb, Sunnyvale, CA, USA., Pollack JL; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; Pionyr Immunotherapeutics, San Francisco, CA, USA., Fries AC; Biological Imaging Development Center and Department of Pathology, University of California, San Francisco, CA, USA., Lwin WW; Diabetes Center, University of California, San Francisco, San Francisco, CA, USA.; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Wigton EJ; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA., Parent AV; Diabetes Center, University of California, San Francisco, San Francisco, CA, USA.; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Kyewski B; Division of Developmental Immunology, Tumor Immunology Program, German Cancer Research Center (DKFZ), Heidelberg, Germany., Erle DJ; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Hogquist KA; Center for Immunology, Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA., Steinmetz LM; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Locksley RM; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA., Anderson MS; Diabetes Center, University of California, San Francisco, San Francisco, CA, USA. mark.anderson@ucsf.edu.; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA. mark.anderson@ucsf.edu.; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA. mark.anderson@ucsf.edu.
Source: Nature [Nature] 2018 Jul; Vol. 559 (7715), pp. 627-631. Date of Electronic Publication: 2018 Jul 18.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
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  Data: Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development.
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  Data: <searchLink fieldCode="AU" term="%22Miller+CN%22">Miller CN</searchLink>; Diabetes Center, University of California, San Francisco, San Francisco, CA, USA.; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Proekt+I%22">Proekt I</searchLink>; Diabetes Center, University of California, San Francisco, San Francisco, CA, USA.; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22von+Moltke+J%22">von Moltke J</searchLink>; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA.; Department of Immunology, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Wells+KL%22">Wells KL</searchLink>; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Rajpurkar+AR%22">Rajpurkar AR</searchLink>; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Center for Immunology, Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Rattay+K%22">Rattay K</searchLink>; Division of Developmental Immunology, Tumor Immunology Program, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Division of Immunology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Khan+IS%22">Khan IS</searchLink>; Diabetes Center, University of California, San Francisco, San Francisco, CA, USA.; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Metzger+TC%22">Metzger TC</searchLink>; 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Diabetes Center, University of California, San Francisco, San Francisco, CA, USA.; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kyewski+B%22">Kyewski B</searchLink>; Division of Developmental Immunology, Tumor Immunology Program, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Erle+DJ%22">Erle DJ</searchLink>; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hogquist+KA%22">Hogquist KA</searchLink>; Center for Immunology, Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Steinmetz+LM%22">Steinmetz LM</searchLink>; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Locksley+RM%22">Locksley RM</searchLink>; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; 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