PK/PD Disconnect Observed with a Reversible Endothelial Lipase Inhibitor.

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Title: PK/PD Disconnect Observed with a Reversible Endothelial Lipase Inhibitor.
Authors: Hangeland JJ; Research and Development, Bristol-Myers Squibb, Princeton, New Jersey 08543, United States., Abell LM; Research and Development, Bristol-Myers Squibb, Princeton, New Jersey 08543, United States., Adam LP; Research and Development, Bristol-Myers Squibb, Princeton, New Jersey 08543, United States., Jiang J; Research and Development, Bristol-Myers Squibb, Princeton, New Jersey 08543, United States., Friends TJ; Research and Development, Bristol-Myers Squibb, Princeton, New Jersey 08543, United States., Haque LE; Research and Development, Bristol-Myers Squibb, Princeton, New Jersey 08543, United States., Neels J; Research and Development, Bristol-Myers Squibb, Princeton, New Jersey 08543, United States., Onorato JM; Research and Development, Bristol-Myers Squibb, Princeton, New Jersey 08543, United States., Chen AYA; Research and Development, Bristol-Myers Squibb, Princeton, New Jersey 08543, United States., Taylor DS; Research and Development, Bristol-Myers Squibb, Princeton, New Jersey 08543, United States., Yin X; Research and Development, Bristol-Myers Squibb, Princeton, New Jersey 08543, United States., Harrity TW; Research and Development, Bristol-Myers Squibb, Princeton, New Jersey 08543, United States., Basso MD; Research and Development, Bristol-Myers Squibb, Princeton, New Jersey 08543, United States., Yang R; Research and Development, Bristol-Myers Squibb, Princeton, New Jersey 08543, United States., Sleph PG; Research and Development, Bristol-Myers Squibb, Princeton, New Jersey 08543, United States., Gordon DA; Research and Development, Bristol-Myers Squibb, Princeton, New Jersey 08543, United States., Huang CS; Research and Development, Bristol-Myers Squibb, Princeton, New Jersey 08543, United States., Wexler RR; Research and Development, Bristol-Myers Squibb, Princeton, New Jersey 08543, United States., Finlay HJ; Research and Development, Bristol-Myers Squibb, Princeton, New Jersey 08543, United States., Lawrence RM; Research and Development, Bristol-Myers Squibb, Princeton, New Jersey 08543, United States.
Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2018 Jun 15; Vol. 9 (7), pp. 673-678. Date of Electronic Publication: 2018 Jun 15 (Print Publication: 2018).
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE
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