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LRRK2 activation in idiopathic Parkinson's disease.

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Title: LRRK2 activation in idiopathic Parkinson's disease.
Authors: Di Maio R; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Ri.MED Foundation, Palermo, Italy., Hoffman EK; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA., Rocha EM; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA., Keeney MT; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA., Sanders LH; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Department of Neurology, Duke University, Durham, NC 27710, USA., De Miranda BR; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA., Zharikov A; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA., Van Laar A; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA., Stepan AF; Worldwide Medicinal Chemistry, Pfizer Worldwide Research and Development, Cambridge, MA 02139, USA., Lanz TA; Worldwide Medicinal Chemistry, Pfizer Worldwide Research and Development, Cambridge, MA 02139, USA., Kofler JK; Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15213, USA., Burton EA; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Geriatric Research, Education and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA., Alessi DR; MRC Protein Phosphorylation and Ubiquitylation Units, University of Dundee, Dundee, Scotland., Hastings TG; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA., Greenamyre JT; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15213, USA. jgreena@pitt.edu.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Geriatric Research, Education and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA.
Source: Science translational medicine [Sci Transl Med] 2018 Jul 25; Vol. 10 (451).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: LRRK2 activation in idiopathic Parkinson's disease.
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  Data: <searchLink fieldCode="AU" term="%22Di+Maio+R%22">Di Maio R</searchLink>; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Ri.MED Foundation, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Hoffman+EK%22">Hoffman EK</searchLink>; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Rocha+EM%22">Rocha EM</searchLink>; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Keeney+MT%22">Keeney MT</searchLink>; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Sanders+LH%22">Sanders LH</searchLink>; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Department of Neurology, Duke University, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22De+Miranda+BR%22">De Miranda BR</searchLink>; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Zharikov+A%22">Zharikov A</searchLink>; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Van+Laar+A%22">Van Laar A</searchLink>; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Stepan+AF%22">Stepan AF</searchLink>; Worldwide Medicinal Chemistry, Pfizer Worldwide Research and Development, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Lanz+TA%22">Lanz TA</searchLink>; Worldwide Medicinal Chemistry, Pfizer Worldwide Research and Development, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Kofler+JK%22">Kofler JK</searchLink>; Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Burton+EA%22">Burton EA</searchLink>; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Geriatric Research, Education and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA.<br /><searchLink fieldCode="AU" term="%22Alessi+DR%22">Alessi DR</searchLink>; MRC Protein Phosphorylation and Ubiquitylation Units, University of Dundee, Dundee, Scotland.<br /><searchLink fieldCode="AU" term="%22Hastings+TG%22">Hastings TG</searchLink>; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Greenamyre+JT%22">Greenamyre JT</searchLink>; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15213, USA. jgreena@pitt.edu.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Geriatric Research, Education and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA.
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  Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2018 Jul 25; Vol. 10 (451).
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      – TitleFull: LRRK2 activation in idiopathic Parkinson's disease.
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