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Biobank-driven genomic discovery yields new insight into atrial fibrillation biology.

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Title: Biobank-driven genomic discovery yields new insight into atrial fibrillation biology.
Authors: Nielsen JB; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Thorolfsdottir RB; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Fritsche LG; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA.; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway.; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Zhou W; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Skov MW; Laboratory of Molecular Cardiology, Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Graham SE; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Herron TJ; Department of Internal Medicine, Center for Arrhythmia Research, University of Michigan, Ann Arbor, MI, USA., McCarthy S; Regeneron Genetics Center, Tarrytown, NY, USA., Schmidt EM; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Sveinbjornsson G; deCODE genetics/Amgen, Inc., Reykjavik, Iceland., Surakka I; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Mathis MR; Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA., Yamazaki M; Medical Device Development and Regulation Research Center, The University of Tokyo, Tokyo, Japan., Crawford RD; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Gabrielsen ME; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway.; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim, Norway., Skogholt AH; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway.; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim, Norway., Holmen OL; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway.; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Cardiology, St. Olav's University Hospital, Trondheim, Norway., Lin M; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Wolford BN; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Dey R; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Dalen H; Department of Medicine, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger, Norway.; Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Cardiology, St. Olav's University Hospital, Trondheim University Hospital, Trondheim, Norway., Sulem P; deCODE genetics/Amgen, Inc., Reykjavik, Iceland., Chung JH; Regeneron Genetics Center, Tarrytown, NY, USA., Backman JD; Regeneron Genetics Center, Tarrytown, NY, USA., Arnar DO; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Department of Medicine, Landspitali - National University Hospital, Reykjavik, Iceland., Thorsteinsdottir U; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Baras A; Regeneron Genetics Center, Tarrytown, NY, USA., O'Dushlaine C; Regeneron Genetics Center, Tarrytown, NY, USA., Holst AG; Laboratory of Molecular Cardiology, Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Wen X; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Hornsby W; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA., Dewey FE; Regeneron Genetics Center, Tarrytown, NY, USA., Boehnke M; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Kheterpal S; Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA., Mukherjee B; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Lee S; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Kang HM; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Holm H; deCODE genetics/Amgen, Inc., Reykjavik, Iceland., Kitzman J; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Shavit JA; Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI, USA., Jalife J; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, Center for Arrhythmia Research, University of Michigan, Ann Arbor, MI, USA.; Fundación Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain., Brummett CM; Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA., Teslovich TM; Regeneron Genetics Center, Tarrytown, NY, USA., Carey DJ; Geisinger Health System, Danville, PA, USA., Gudbjartsson DF; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland., Stefansson K; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Abecasis GR; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim, Norway. goncalo@umich.edu.; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA. goncalo@umich.edu., Hveem K; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway. kristian.hveem@ntnu.no.; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim, Norway. kristian.hveem@ntnu.no.; Department of Medicine, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger, Norway. kristian.hveem@ntnu.no., Willer CJ; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA. cristen@umich.edu.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA. cristen@umich.edu.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA. cristen@umich.edu.
Source: Nature genetics [Nat Genet] 2018 Sep; Vol. 50 (9), pp. 1234-1239. Date of Electronic Publication: 2018 Jul 30.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Biobank-driven genomic discovery yields new insight into atrial fibrillation biology.
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  Data: <searchLink fieldCode="AU" term="%22Nielsen+JB%22">Nielsen JB</searchLink>; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Thorolfsdottir+RB%22">Thorolfsdottir RB</searchLink>; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Fritsche+LG%22">Fritsche LG</searchLink>; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA.; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway.; K.G. 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Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim, Norway. goncalo@umich.edu.; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA. goncalo@umich.edu.<br /><searchLink fieldCode="AU" term="%22Hveem+K%22">Hveem K</searchLink>; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway. kristian.hveem@ntnu.no.; K.G. 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          Name:
            NameFull: Stefansson K
      – PersonEntity:
          Name:
            NameFull: Abecasis GR
      – PersonEntity:
          Name:
            NameFull: Hveem K
      – PersonEntity:
          Name:
            NameFull: Willer CJ
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 09
              Text: 2018 Sep
              Type: published
              Y: 2018
          Identifiers:
            – Type: issn-electronic
              Value: 1546-1718
          Numbering:
            – Type: volume
              Value: 50
            – Type: issue
              Value: 9
          Titles:
            – TitleFull: Nature genetics
              Type: main
ResultId 1