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Drosophila CaV2 channels harboring human migraine mutations cause synapse hyperexcitability that can be suppressed by inhibition of a Ca2+ store release pathway.

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Title: Drosophila CaV2 channels harboring human migraine mutations cause synapse hyperexcitability that can be suppressed by inhibition of a Ca2+ store release pathway.
Authors: Brusich DJ; Department of Anatomy and Cell Biology, University of Iowa Carver College of Medicine, Iowa City, IA, United States of America., Spring AM; Department of Anatomy and Cell Biology, University of Iowa Carver College of Medicine, Iowa City, IA, United States of America.; Interdisciplinary Graduate Program in Genetics, University of Iowa, Iowa City, IA, United States of America., James TD; Department of Anatomy and Cell Biology, University of Iowa Carver College of Medicine, Iowa City, IA, United States of America.; Interdisciplinary Graduate Program in Neuroscience, University of Iowa, Iowa City, IA, United States of America., Yeates CJ; Department of Anatomy and Cell Biology, University of Iowa Carver College of Medicine, Iowa City, IA, United States of America.; Interdisciplinary Graduate Program in Neuroscience, University of Iowa, Iowa City, IA, United States of America., Helms TH; Department of Anatomy and Cell Biology, University of Iowa Carver College of Medicine, Iowa City, IA, United States of America., Frank CA; Department of Anatomy and Cell Biology, University of Iowa Carver College of Medicine, Iowa City, IA, United States of America.; Interdisciplinary Graduate Program in Genetics, University of Iowa, Iowa City, IA, United States of America.; Interdisciplinary Graduate Program in Neuroscience, University of Iowa, Iowa City, IA, United States of America.
Source: PLoS genetics [PLoS Genet] 2018 Aug 06; Vol. 14 (8), pp. e1007577. Date of Electronic Publication: 2018 Aug 06 (Print Publication: 2018).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Drosophila CaV2 channels harboring human migraine mutations cause synapse hyperexcitability that can be suppressed by inhibition of a Ca2+ store release pathway.
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