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Genetic and transcriptional evolution alters cancer cell line drug response.

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Title: Genetic and transcriptional evolution alters cancer cell line drug response.
Authors: Ben-David U; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Siranosian B; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Ha G; Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Dana-Farber Cancer Institute, Boston, MA, USA., Tang H; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Oren Y; Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA., Hinohara K; Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Dana-Farber Cancer Institute, Boston, MA, USA., Strathdee CA; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Dempster J; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Lyons NJ; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Burns R; Dana-Farber Cancer Institute, Boston, MA, USA., Nag A; Dana-Farber Cancer Institute, Boston, MA, USA., Kugener G; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Cimini B; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Tsvetkov P; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Maruvka YE; Broad Institute of Harvard and MIT, Cambridge, MA, USA., O'Rourke R; Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Dana-Farber Cancer Institute, Boston, MA, USA., Garrity A; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Tubelli AA; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Bandopadhayay P; Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Tsherniak A; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Vazquez F; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Wong B; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Birger C; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Ghandi M; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Thorner AR; Dana-Farber Cancer Institute, Boston, MA, USA., Bittker JA; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Meyerson M; Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Getz G; Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA., Beroukhim R; Broad Institute of Harvard and MIT, Cambridge, MA, USA. rameen_beroukhim@dfci.harvard.edu.; Dana-Farber Cancer Institute, Boston, MA, USA. rameen_beroukhim@dfci.harvard.edu.; Harvard Medical School, Boston, MA, USA. rameen_beroukhim@dfci.harvard.edu.; Brigham and Women's Hospital, Boston, MA, USA. rameen_beroukhim@dfci.harvard.edu., Golub TR; Broad Institute of Harvard and MIT, Cambridge, MA, USA. golub@broadinstitute.org.; Dana-Farber Cancer Institute, Boston, MA, USA. golub@broadinstitute.org.; Harvard Medical School, Boston, MA, USA. golub@broadinstitute.org.; Howard Hughes Medical Institute, Chevy Chase, MD, USA. golub@broadinstitute.org.
Source: Nature [Nature] 2018 Aug; Vol. 560 (7718), pp. 325-330. Date of Electronic Publication: 2018 Aug 08.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
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