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The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target.

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Title: The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target.
Authors: Petyuk VA; Biological Sciences Division and Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA, USA., Chang R; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Ramirez-Restrepo M; Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, USA., Beckmann ND; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Henrion MYR; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Piehowski PD; Biological Sciences Division and Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA, USA., Zhu K; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Wang S; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Clarke J; Food Science and Technology Department, University of Nebraska-Lincoln, Lincoln, NE, USA., Huentelman MJ; Neurogenomics Division, The Translational Genomics Research Institute, Phoenix, AZ, USA., Xie F; Biological Sciences Division and Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA, USA., Andreev V; Arbor Research Collaborative for Health, 340 E Huron St # 300, Ann Arbor, MI, USA., Engel A; Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, USA., Guettoche T; Roche Sequencing, 4300 Hacienda Drive, Pleasanton, CA, USA., Navarro L; Roche Sequencing, 4300 Hacienda Drive, Pleasanton, CA, USA., De Jager P; Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York, NY, USA.; New York Genome Center, New York NY, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA., Schneider JA; Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, IL, USA., Morris CM; Newcastle Brain Tissue Resource, Institute of Neuroscience, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne, UK., McKeith IG; NIHR Biomedical Research Centre, Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK., Perry RH; Neuropathology and Cellular Pathology, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne, UK., Lovestone S; University of Oxford, Medical Sciences Division, Department of Psychiatry, Warneford Hospital, Oxford, UK., Woltjer RL; Neuropathology Core of the Layton Aging and Alzheimer’s Disease Center, Oregon Health and Science University, Portland, OR, USA., Beach TG; Banner Sun Health Research Institute, Sun City, AZ, USA., Sue LI; Banner Sun Health Research Institute, Sun City, AZ, USA., Serrano GE; Banner Sun Health Research Institute, Sun City, AZ, USA., Lieberman AP; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Albin RL; Department of Neurology, University of Michigan, Ann Arbor, MI, USA.; Geriatrics Research, Education, and Clinical Center, VAAAHS, Ann Arbor, MI, USA., Ferrer I; Department of Pathology and Experimental Therapeutics, University of Barcelona; CIBERNED; Hospitalet de Llobregat, Spain., Mash DC; Department of Neurology, University of Miami Miller School of Medicine, Miami, FL, USA., Hulette CM; Department of Pathology, Division of Neuropathology, Duke University Medical Center, Durham, NC, USA., Ervin JF; Kathleen Price Bryan Brain Bank, Department of Medicine, Division of Neurology, Duke University, Durham, NC, USA., Reiman EM; The Arizona Alzheimer’s Consortium, Phoenix, Arizona, USA.; Banner Alzheimer’s Institute, Phoenix, Arizona, USA., Hardy JA; Department of Molecular Neuroscience and Reta Lila Research Laboratories, University College London Institute of Neurology, London, UK., Bennett DA; Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, IL, USA., Schadt E; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Smith RD; Biological Sciences Division and Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA, USA., Myers AJ; Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.; Interdepartmental Program in Neuroscience, University of Miami Miller School of Medicine, Miami, FL, USA.; Interdepartmental Program in Human Genetics and Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
Source: Brain : a journal of neurology [Brain] 2018 Sep 01; Vol. 141 (9), pp. 2721-2739.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target.
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Department of Pathology, Division of Neuropathology, Duke University Medical Center, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Ervin+JF%22">Ervin JF</searchLink>; Kathleen Price Bryan Brain Bank, Department of Medicine, Division of Neurology, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Reiman+EM%22">Reiman EM</searchLink>; The Arizona Alzheimer’s Consortium, Phoenix, Arizona, USA.; Banner Alzheimer’s Institute, Phoenix, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Hardy+JA%22">Hardy JA</searchLink>; Department of Molecular Neuroscience and Reta Lila Research Laboratories, University College London Institute of Neurology, London, UK.<br /><searchLink fieldCode="AU" term="%22Bennett+DA%22">Bennett DA</searchLink>; Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Schadt+E%22">Schadt E</searchLink>; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Smith+RD%22">Smith RD</searchLink>; 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