View in EDS HTML Full Text PDF Full Text

SIRT6 haploinsufficiency induces BRAFV600E melanoma cell resistance to MAPK inhibitors via IGF signalling.

Saved in:
Bibliographic Details
Title: SIRT6 haploinsufficiency induces BRAFV600E melanoma cell resistance to MAPK inhibitors via IGF signalling.
Authors: Strub T; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.; Department of Dermatology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA., Ghiraldini FG; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.; Department of Dermatology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA., Carcamo S; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.; Department of Dermatology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA., Li M; Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, 02129, USA., Wroblewska A; Department of Genetics and Genomic Sciences, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA., Singh R; Department of Dermatology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.; Department of Pathology, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA., Goldberg MS; Department of Dermatology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.; Department of Pathology, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA., Hasson D; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.; Department of Dermatology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA., Wang Z; Department of Pharmacological Sciences, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA., Gallagher SJ; Centenary Institute, Camperdown NSW 2050, The University of Sydney, Sydney, Australia.; Melanoma Institute Australia, Wollstonecraft NSW 2065, The University of Sydney, Sydney, Australia., Hersey P; Centenary Institute, Camperdown NSW 2050, The University of Sydney, Sydney, Australia.; Melanoma Institute Australia, Wollstonecraft NSW 2065, The University of Sydney, Sydney, Australia., Ma'ayan A; Department of Pharmacological Sciences, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA., Long GV; Melanoma Institute Australia, Wollstonecraft NSW 2065, The University of Sydney, Sydney, Australia.; Sydney Medical School, University of Sydney, Sydney, NSW, 2050, Australia.; Royal North Shore Hospital, Sydney, NSW, 2065, Australia., Scolyer RA; Melanoma Institute Australia, Wollstonecraft NSW 2065, The University of Sydney, Sydney, Australia.; Sydney Medical School, University of Sydney, Sydney, NSW, 2050, Australia.; Royal Prince Alfred Hospital, Sydney, NSW, 2050, Australia., Brown B; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.; Department of Genetics and Genomic Sciences, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA., Zheng B; Centenary Institute, Camperdown NSW 2050, The University of Sydney, Sydney, Australia., Bernstein E; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA. emily.bernstein@mssm.edu.; Department of Dermatology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA. emily.bernstein@mssm.edu.; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA. emily.bernstein@mssm.edu.
Source: Nature communications [Nat Commun] 2018 Aug 24; Vol. 9 (1), pp. 3440. Date of Electronic Publication: 2018 Aug 24.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 30143629
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: SIRT6 haploinsufficiency induces BRAF<superscript>V600E</superscript> melanoma cell resistance to MAPK inhibitors via IGF signalling.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Strub+T%22">Strub T</searchLink>; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.; Department of Dermatology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.<br /><searchLink fieldCode="AU" term="%22Ghiraldini+FG%22">Ghiraldini FG</searchLink>; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.; Department of Dermatology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.<br /><searchLink fieldCode="AU" term="%22Carcamo+S%22">Carcamo S</searchLink>; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.; Department of Dermatology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.<br /><searchLink fieldCode="AU" term="%22Li+M%22">Li M</searchLink>; Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, 02129, USA.<br /><searchLink fieldCode="AU" term="%22Wroblewska+A%22">Wroblewska A</searchLink>; Department of Genetics and Genomic Sciences, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.<br /><searchLink fieldCode="AU" term="%22Singh+R%22">Singh R</searchLink>; Department of Dermatology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.; Department of Pathology, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.<br /><searchLink fieldCode="AU" term="%22Goldberg+MS%22">Goldberg MS</searchLink>; Department of Dermatology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.; Department of Pathology, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.<br /><searchLink fieldCode="AU" term="%22Hasson+D%22">Hasson D</searchLink>; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.; Department of Dermatology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Department of Pharmacological Sciences, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.<br /><searchLink fieldCode="AU" term="%22Gallagher+SJ%22">Gallagher SJ</searchLink>; Centenary Institute, Camperdown NSW 2050, The University of Sydney, Sydney, Australia.; Melanoma Institute Australia, Wollstonecraft NSW 2065, The University of Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Hersey+P%22">Hersey P</searchLink>; Centenary Institute, Camperdown NSW 2050, The University of Sydney, Sydney, Australia.; Melanoma Institute Australia, Wollstonecraft NSW 2065, The University of Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Ma'ayan+A%22">Ma'ayan A</searchLink>; Department of Pharmacological Sciences, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.<br /><searchLink fieldCode="AU" term="%22Long+GV%22">Long GV</searchLink>; Melanoma Institute Australia, Wollstonecraft NSW 2065, The University of Sydney, Sydney, Australia.; Sydney Medical School, University of Sydney, Sydney, NSW, 2050, Australia.; Royal North Shore Hospital, Sydney, NSW, 2065, Australia.<br /><searchLink fieldCode="AU" term="%22Scolyer+RA%22">Scolyer RA</searchLink>; Melanoma Institute Australia, Wollstonecraft NSW 2065, The University of Sydney, Sydney, Australia.; Sydney Medical School, University of Sydney, Sydney, NSW, 2050, Australia.; Royal Prince Alfred Hospital, Sydney, NSW, 2050, Australia.<br /><searchLink fieldCode="AU" term="%22Brown+B%22">Brown B</searchLink>; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.; Department of Genetics and Genomic Sciences, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.<br /><searchLink fieldCode="AU" term="%22Zheng+B%22">Zheng B</searchLink>; Centenary Institute, Camperdown NSW 2050, The University of Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Bernstein+E%22">Bernstein E</searchLink>; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA. emily.bernstein@mssm.edu.; Department of Dermatology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA. emily.bernstein@mssm.edu.; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA. emily.bernstein@mssm.edu.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2018 Aug 24; Vol. 9 (1), pp. 3440. <i>Date of Electronic Publication: </i>2018 Aug 24.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=30143629
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41467-018-05966-z
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 3440
    Titles:
      – TitleFull: SIRT6 haploinsufficiency induces BRAFV600E melanoma cell resistance to MAPK inhibitors via IGF signalling.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Strub T
      – PersonEntity:
          Name:
            NameFull: Ghiraldini FG
      – PersonEntity:
          Name:
            NameFull: Carcamo S
      – PersonEntity:
          Name:
            NameFull: Li M
      – PersonEntity:
          Name:
            NameFull: Wroblewska A
      – PersonEntity:
          Name:
            NameFull: Singh R
      – PersonEntity:
          Name:
            NameFull: Goldberg MS
      – PersonEntity:
          Name:
            NameFull: Hasson D
      – PersonEntity:
          Name:
            NameFull: Wang Z
      – PersonEntity:
          Name:
            NameFull: Gallagher SJ
      – PersonEntity:
          Name:
            NameFull: Hersey P
      – PersonEntity:
          Name:
            NameFull: Ma'ayan A
      – PersonEntity:
          Name:
            NameFull: Long GV
      – PersonEntity:
          Name:
            NameFull: Scolyer RA
      – PersonEntity:
          Name:
            NameFull: Brown B
      – PersonEntity:
          Name:
            NameFull: Zheng B
      – PersonEntity:
          Name:
            NameFull: Bernstein E
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 24
              M: 08
              Text: 2018 Aug 24
              Type: published
              Y: 2018
          Identifiers:
            – Type: issn-electronic
              Value: 2041-1723
          Numbering:
            – Type: volume
              Value: 9
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Nature communications
              Type: main
ResultId 1