A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers.

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Title: A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers.
Authors: Mosley JD; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA. jonathan.d.mosley@vanderbilt.edu.; Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, 37232, USA. jonathan.d.mosley@vanderbilt.edu., Feng Q; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Wells QS; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Van Driest SL; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Shaffer CM; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Edwards TL; Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Bastarache L; Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Wei WQ; Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Davis LK; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., McCarty CA; Essentia Institute of Rural Health, Duluth, MN, 55805, USA., Thompson W; Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Chute CG; Schools of Medicine, Public Health, and Nursing, Johns Hopkins University, Baltimore, MD, 21205, USA., Jarvik GP; Department of Medicine (Medical Genetics), University of Washington, Seattle, WA, 98195, USA., Gordon AS; Department of Medicine (Medical Genetics), University of Washington, Seattle, WA, 98195, USA., Palmer MR; Department of Medicine (Medical Genetics), University of Washington, Seattle, WA, 98195, USA., Crosslin DR; Departments of Biomedical Informatics and Medical Education, University of Washington, Seattle, WA, 98195, USA., Larson EB; Department of Medicine (Medical Genetics), University of Washington, Seattle, WA, 98195, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, 98101, USA., Carrell DS; Kaiser Permanente Washington Health Research Institute, Seattle, WA, 98101, USA., Kullo IJ; Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, 55905, USA., Pacheco JA; Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA., Peissig PL; Biomedical Informatics Research Center, Marshfield Clinic Research Institute, Marshfield, WI, 54449, USA., Brilliant MH; Center for Human Genetics, Marshfield Clinic Research Institute, Marshfield, WI, 54449, USA., Linneman JG; Biomedical Informatics Research Center, Marshfield Clinic Research Institute, Marshfield, WI, 54449, USA., Namjou B; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA., Williams MS; Genomic Medicine Institute, Geisinger Health System, Danville, PA, 17822, USA., Ritchie MD; Biomedical and Translational Informatics, Geisinger Health System, Danville, PA, 17822, USA., Borthwick KM; Biomedical and Translational Informatics, Geisinger Health System, Danville, PA, 17822, USA., Verma SS; Biomedical and Translational Informatics, Geisinger Health System, Danville, PA, 17822, USA., Karnes JH; Department of Pharmacy Practice and Science, University of Arizona College of Pharmacy, Tucson, Arizona, 85721, USA., Weiss ST; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA., Wang TJ; Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Stein CM; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Denny JC; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.; Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Roden DM; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.; Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.; Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
Source: Nature communications [Nat Commun] 2018 Aug 30; Vol. 9 (1), pp. 3522. Date of Electronic Publication: 2018 Aug 30.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers.
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  Data: <searchLink fieldCode="AU" term="%22Mosley+JD%22">Mosley JD</searchLink>; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA. jonathan.d.mosley@vanderbilt.edu.; Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, 37232, USA. jonathan.d.mosley@vanderbilt.edu.<br /><searchLink fieldCode="AU" term="%22Feng+Q%22">Feng Q</searchLink>; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.<br /><searchLink fieldCode="AU" term="%22Wells+QS%22">Wells QS</searchLink>; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.<br /><searchLink fieldCode="AU" term="%22Van+Driest+SL%22">Van Driest SL</searchLink>; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.<br /><searchLink fieldCode="AU" term="%22Shaffer+CM%22">Shaffer CM</searchLink>; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.<br /><searchLink fieldCode="AU" term="%22Edwards+TL%22">Edwards TL</searchLink>; Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.<br /><searchLink fieldCode="AU" term="%22Bastarache+L%22">Bastarache L</searchLink>; Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.<br /><searchLink fieldCode="AU" term="%22Wei+WQ%22">Wei WQ</searchLink>; Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.<br /><searchLink fieldCode="AU" term="%22Davis+LK%22">Davis LK</searchLink>; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.<br /><searchLink fieldCode="AU" term="%22McCarty+CA%22">McCarty CA</searchLink>; Essentia Institute of Rural Health, Duluth, MN, 55805, USA.<br /><searchLink fieldCode="AU" term="%22Thompson+W%22">Thompson W</searchLink>; Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.<br /><searchLink fieldCode="AU" term="%22Chute+CG%22">Chute CG</searchLink>; Schools of Medicine, Public Health, and Nursing, Johns Hopkins University, Baltimore, MD, 21205, USA.<br /><searchLink fieldCode="AU" term="%22Jarvik+GP%22">Jarvik GP</searchLink>; Department of Medicine (Medical Genetics), University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Gordon+AS%22">Gordon AS</searchLink>; Department of Medicine (Medical Genetics), University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Palmer+MR%22">Palmer MR</searchLink>; Department of Medicine (Medical Genetics), University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Crosslin+DR%22">Crosslin DR</searchLink>; Departments of Biomedical Informatics and Medical Education, University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Larson+EB%22">Larson EB</searchLink>; Department of Medicine (Medical Genetics), University of Washington, Seattle, WA, 98195, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, 98101, USA.<br /><searchLink fieldCode="AU" term="%22Carrell+DS%22">Carrell DS</searchLink>; Kaiser Permanente Washington Health Research Institute, Seattle, WA, 98101, USA.<br /><searchLink fieldCode="AU" term="%22Kullo+IJ%22">Kullo IJ</searchLink>; Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Pacheco+JA%22">Pacheco JA</searchLink>; Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.<br /><searchLink fieldCode="AU" term="%22Peissig+PL%22">Peissig PL</searchLink>; Biomedical Informatics Research Center, Marshfield Clinic Research Institute, Marshfield, WI, 54449, USA.<br /><searchLink fieldCode="AU" term="%22Brilliant+MH%22">Brilliant MH</searchLink>; Center for Human Genetics, Marshfield Clinic Research Institute, Marshfield, WI, 54449, USA.<br /><searchLink fieldCode="AU" term="%22Linneman+JG%22">Linneman JG</searchLink>; Biomedical Informatics Research Center, Marshfield Clinic Research Institute, Marshfield, WI, 54449, USA.<br /><searchLink fieldCode="AU" term="%22Namjou+B%22">Namjou B</searchLink>; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.<br /><searchLink fieldCode="AU" term="%22Williams+MS%22">Williams MS</searchLink>; Genomic Medicine Institute, Geisinger Health System, Danville, PA, 17822, USA.<br /><searchLink fieldCode="AU" term="%22Ritchie+MD%22">Ritchie MD</searchLink>; Biomedical and Translational Informatics, Geisinger Health System, Danville, PA, 17822, USA.<br /><searchLink fieldCode="AU" term="%22Borthwick+KM%22">Borthwick KM</searchLink>; Biomedical and Translational Informatics, Geisinger Health System, Danville, PA, 17822, USA.<br /><searchLink fieldCode="AU" term="%22Verma+SS%22">Verma SS</searchLink>; Biomedical and Translational Informatics, Geisinger Health System, Danville, PA, 17822, USA.<br /><searchLink fieldCode="AU" term="%22Karnes+JH%22">Karnes JH</searchLink>; Department of Pharmacy Practice and Science, University of Arizona College of Pharmacy, Tucson, Arizona, 85721, USA.<br /><searchLink fieldCode="AU" term="%22Weiss+ST%22">Weiss ST</searchLink>; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.<br /><searchLink fieldCode="AU" term="%22Wang+TJ%22">Wang TJ</searchLink>; Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.<br /><searchLink fieldCode="AU" term="%22Stein+CM%22">Stein CM</searchLink>; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.<br /><searchLink fieldCode="AU" term="%22Denny+JC%22">Denny JC</searchLink>; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.; Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.<br /><searchLink fieldCode="AU" term="%22Roden+DM%22">Roden DM</searchLink>; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.; Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.; Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2018 Aug 30; Vol. 9 (1), pp. 3522. <i>Date of Electronic Publication: </i>2018 Aug 30.
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