Enzymatic chokepoints and synergistic drug targets in the sterol biosynthesis pathway of Naegleria fowleri.
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| Title: | Enzymatic chokepoints and synergistic drug targets in the sterol biosynthesis pathway of Naegleria fowleri. |
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| Authors: | Zhou W; Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas, United States of America., Debnath A; Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States of America., Jennings G; Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States of America., Hahn HJ; Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States of America., Vanderloop BH; Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas, United States of America., Chaudhuri M; Department of Microbiology and Immunology, Meharry Medical College, Nashville, Tennessee, United States of America., Nes WD; Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas, United States of America., Podust LM; Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States of America. |
| Source: | PLoS pathogens [PLoS Pathog] 2018 Sep 13; Vol. 14 (9), pp. e1007245. Date of Electronic Publication: 2018 Sep 13 (Print Publication: 2018). |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1553-7374 |
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| DOI: | 10.1371/journal.ppat.1007245 |
