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Extrapolation of praziquantel pharmacokinetics to a pediatric population: a cautionary tale.

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Title: Extrapolation of praziquantel pharmacokinetics to a pediatric population: a cautionary tale.
Authors: Bonate PL; Astellas, 1 Astellas Way, Northbrook, IL, 60062, USA. peter.bonate@astellas.com., Wang T; Astellas, 1 Astellas Way, Northbrook, IL, 60062, USA.; Alkermes, Waltham, MA, 02451, USA., Passier P; Astellas, 1 Astellas Way, Northbrook, IL, 60062, USA.; Galapagos BV, Zernikedreef 16, Leiden, The Netherlands., Bagchus W; Merck Serono SA, Merck Institute for Pharmacometrics (A Subsidiary of Merck KGaA, Darmstadt, Germany), Lausanne, Switzerland., Burt H; Simcyp (a Certara company), Blades Enterprise Centre, John Street, Sheffield, S2 4SU, UK., Lüpfert C; Merck KGaA, Translational Quantitative Pharmacology, Frankfurter Str. 250, 64293, Darmstadt, Germany., Abla N; Merck Global Health Institute, Ares Trading S.A. (A Subsidiary of Merck KGaA, Darmstadt, Germany), 1262, Eysins, Switzerland., Kovac J; Swiss Tropical and Public Health Institute, Socinstr. 57, CH-4002, Basel, Switzerland.; University of Basel, Basel, Switzerland., Keiser J; Swiss Tropical and Public Health Institute, Socinstr. 57, CH-4002, Basel, Switzerland.; University of Basel, Basel, Switzerland.
Source: Journal of pharmacokinetics and pharmacodynamics [J Pharmacokinet Pharmacodyn] 2018 Oct; Vol. 45 (5), pp. 747-762. Date of Electronic Publication: 2018 Sep 14.
Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101096520 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-8744 (Electronic) Linking ISSN: 1567567X NLM ISO Abbreviation: J Pharmacokinet Pharmacodyn Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Extrapolation of praziquantel pharmacokinetics to a pediatric population: a cautionary tale.
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  Data: <searchLink fieldCode="AU" term="%22Bonate+PL%22">Bonate PL</searchLink>; Astellas, 1 Astellas Way, Northbrook, IL, 60062, USA. peter.bonate@astellas.com.<br /><searchLink fieldCode="AU" term="%22Wang+T%22">Wang T</searchLink>; Astellas, 1 Astellas Way, Northbrook, IL, 60062, USA.; Alkermes, Waltham, MA, 02451, USA.<br /><searchLink fieldCode="AU" term="%22Passier+P%22">Passier P</searchLink>; Astellas, 1 Astellas Way, Northbrook, IL, 60062, USA.; Galapagos BV, Zernikedreef 16, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bagchus+W%22">Bagchus W</searchLink>; Merck Serono SA, Merck Institute for Pharmacometrics (A Subsidiary of Merck KGaA, Darmstadt, Germany), Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Burt+H%22">Burt H</searchLink>; Simcyp (a Certara company), Blades Enterprise Centre, John Street, Sheffield, S2 4SU, UK.<br /><searchLink fieldCode="AU" term="%22Lüpfert+C%22">Lüpfert C</searchLink>; Merck KGaA, Translational Quantitative Pharmacology, Frankfurter Str. 250, 64293, Darmstadt, Germany.<br /><searchLink fieldCode="AU" term="%22Abla+N%22">Abla N</searchLink>; Merck Global Health Institute, Ares Trading S.A. (A Subsidiary of Merck KGaA, Darmstadt, Germany), 1262, Eysins, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kovac+J%22">Kovac J</searchLink>; Swiss Tropical and Public Health Institute, Socinstr. 57, CH-4002, Basel, Switzerland.; University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Keiser+J%22">Keiser J</searchLink>; Swiss Tropical and Public Health Institute, Socinstr. 57, CH-4002, Basel, Switzerland.; University of Basel, Basel, Switzerland.
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  Data: <searchLink fieldCode="JN" term="%22101096520%22">Journal of pharmacokinetics and pharmacodynamics</searchLink> [J Pharmacokinet Pharmacodyn] 2018 Oct; Vol. 45 (5), pp. 747-762. <i>Date of Electronic Publication: </i>2018 Sep 14.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101096520 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-8744 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221567567X%22">1567567X </searchLink><i>NLM ISO Abbreviation: </i>J Pharmacokinet Pharmacodyn <i>Subsets: </i>MEDLINE
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