A multicenter phase 1 study of solitomab (MT110, AMG 110), a bispecific EpCAM/CD3 T-cell engager (BiTE®) antibody construct, in patients with refractory solid tumors.

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Title: A multicenter phase 1 study of solitomab (MT110, AMG 110), a bispecific EpCAM/CD3 T-cell engager (BiTE®) antibody construct, in patients with refractory solid tumors.
Authors: Kebenko M; Department of Oncology/Hematology, Bone Marrow Transplantation and Section Pneumology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Goebeler ME; Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, Würzburg, Germany., Wolf M; Clinic Kassel, Kassel, Germany., Hasenburg A; Department of Gynecology, Johannes Gutenberg University Medical Center, Mainz, Germany., Seggewiss-Bernhardt R; Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, Würzburg, Germany., Ritter B; Clinic Kassel, Kassel, Germany., Rautenberg B; Department of Gynecology, Johannes Gutenberg University Medical Center, Mainz, Germany., Atanackovic D; Department of Oncology/Hematology, Bone Marrow Transplantation and Section Pneumology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Kratzer A; Amgen Research (Munich) GmbH, Munich, Germany., Rottman JB; Amgen Inc., Thousand Oaks, CA, USA., Friedrich M; Amgen Research (Munich) GmbH, Munich, Germany., Vieser E; Amgen Research (Munich) GmbH, Munich, Germany., Elm S; Amgen Research (Munich) GmbH, Munich, Germany., Patzak I; Amgen Research (Munich) GmbH, Munich, Germany., Wessiepe D; Metronomia Clinical Research GmbH, Munich, Germany., Stienen S; Amgen Research (Munich) GmbH, Munich, Germany., Fiedler W; Department of Oncology/Hematology, Bone Marrow Transplantation and Section Pneumology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Source: Oncoimmunology [Oncoimmunology] 2018 Apr 18; Vol. 7 (8), pp. e1450710. Date of Electronic Publication: 2018 Apr 18 (Print Publication: 2018).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101570526 Publication Model: eCollection Cited Medium: Print ISSN: 2162-4011 (Print) Linking ISSN: 21624011 NLM ISO Abbreviation: Oncoimmunology Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: A multicenter phase 1 study of solitomab (MT110, AMG 110), a bispecific EpCAM/CD3 T-cell engager (BiTE®) antibody construct, in patients with refractory solid tumors.
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  Data: <searchLink fieldCode="AU" term="%22Kebenko+M%22">Kebenko M</searchLink>; Department of Oncology/Hematology, Bone Marrow Transplantation and Section Pneumology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Goebeler+ME%22">Goebeler ME</searchLink>; Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Wolf+M%22">Wolf M</searchLink>; Clinic Kassel, Kassel, Germany.<br /><searchLink fieldCode="AU" term="%22Hasenburg+A%22">Hasenburg A</searchLink>; Department of Gynecology, Johannes Gutenberg University Medical Center, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Seggewiss-Bernhardt+R%22">Seggewiss-Bernhardt R</searchLink>; Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Ritter+B%22">Ritter B</searchLink>; Clinic Kassel, Kassel, Germany.<br /><searchLink fieldCode="AU" term="%22Rautenberg+B%22">Rautenberg B</searchLink>; Department of Gynecology, Johannes Gutenberg University Medical Center, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Atanackovic+D%22">Atanackovic D</searchLink>; Department of Oncology/Hematology, Bone Marrow Transplantation and Section Pneumology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Kratzer+A%22">Kratzer A</searchLink>; Amgen Research (Munich) GmbH, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Rottman+JB%22">Rottman JB</searchLink>; Amgen Inc., Thousand Oaks, CA, USA.<br /><searchLink fieldCode="AU" term="%22Friedrich+M%22">Friedrich M</searchLink>; Amgen Research (Munich) GmbH, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Vieser+E%22">Vieser E</searchLink>; Amgen Research (Munich) GmbH, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Elm+S%22">Elm S</searchLink>; Amgen Research (Munich) GmbH, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Patzak+I%22">Patzak I</searchLink>; Amgen Research (Munich) GmbH, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Wessiepe+D%22">Wessiepe D</searchLink>; Metronomia Clinical Research GmbH, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Stienen+S%22">Stienen S</searchLink>; Amgen Research (Munich) GmbH, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Fiedler+W%22">Fiedler W</searchLink>; Department of Oncology/Hematology, Bone Marrow Transplantation and Section Pneumology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
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