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Cobimetinib and trametinib inhibit platelet MEK but do not cause platelet dysfunction.

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Title: Cobimetinib and trametinib inhibit platelet MEK but do not cause platelet dysfunction.
Authors: Unsworth AJ; a Institute for Cardiovascular and Metabolic Research , University of Reading, School of Biological Sciences , Reading , UK., Bye AP; a Institute for Cardiovascular and Metabolic Research , University of Reading, School of Biological Sciences , Reading , UK., Kriek N; a Institute for Cardiovascular and Metabolic Research , University of Reading, School of Biological Sciences , Reading , UK., Sage T; a Institute for Cardiovascular and Metabolic Research , University of Reading, School of Biological Sciences , Reading , UK., Osborne AA; a Institute for Cardiovascular and Metabolic Research , University of Reading, School of Biological Sciences , Reading , UK., Donaghy D; b Department of Microbiology Immunology and Pathology , Colorado State University , Fort Collins , CO , USA., Gibbins JM; a Institute for Cardiovascular and Metabolic Research , University of Reading, School of Biological Sciences , Reading , UK.
Source: Platelets [Platelets] 2019; Vol. 30 (6), pp. 762-772. Date of Electronic Publication: 2018 Sep 25.
Publication Type: Journal Article
Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9208117 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1369-1635 (Electronic) Linking ISSN: 09537104 NLM ISO Abbreviation: Platelets Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cobimetinib and trametinib inhibit platelet MEK but do not cause platelet dysfunction.
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  Data: <searchLink fieldCode="AU" term="%22Unsworth+AJ%22">Unsworth AJ</searchLink>; a Institute for Cardiovascular and Metabolic Research , University of Reading, School of Biological Sciences , Reading , UK.<br /><searchLink fieldCode="AU" term="%22Bye+AP%22">Bye AP</searchLink>; a Institute for Cardiovascular and Metabolic Research , University of Reading, School of Biological Sciences , Reading , UK.<br /><searchLink fieldCode="AU" term="%22Kriek+N%22">Kriek N</searchLink>; a Institute for Cardiovascular and Metabolic Research , University of Reading, School of Biological Sciences , Reading , UK.<br /><searchLink fieldCode="AU" term="%22Sage+T%22">Sage T</searchLink>; a Institute for Cardiovascular and Metabolic Research , University of Reading, School of Biological Sciences , Reading , UK.<br /><searchLink fieldCode="AU" term="%22Osborne+AA%22">Osborne AA</searchLink>; a Institute for Cardiovascular and Metabolic Research , University of Reading, School of Biological Sciences , Reading , UK.<br /><searchLink fieldCode="AU" term="%22Donaghy+D%22">Donaghy D</searchLink>; b Department of Microbiology Immunology and Pathology , Colorado State University , Fort Collins , CO , USA.<br /><searchLink fieldCode="AU" term="%22Gibbins+JM%22">Gibbins JM</searchLink>; a Institute for Cardiovascular and Metabolic Research , University of Reading, School of Biological Sciences , Reading , UK.
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  Data: <searchLink fieldCode="JN" term="%229208117%22">Platelets</searchLink> [Platelets] 2019; Vol. 30 (6), pp. 762-772. <i>Date of Electronic Publication: </i>2018 Sep 25.
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