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N-acetylcysteine add-on treatment leads to an improvement of fornix white matter integrity in early psychosis: a double-blind randomized placebo-controlled trial.

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Title: N-acetylcysteine add-on treatment leads to an improvement of fornix white matter integrity in early psychosis: a double-blind randomized placebo-controlled trial.
Authors: Klauser P; Service of General Psychiatry, Department of Psychiatry, Lausanne University Hospital (CHUV), Lausanne, Switzerland.; Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital (CHUV), Lausanne, Switzerland.; National Center of Competence in Research (NCCR) 'SYNAPSY - The Synaptic Bases of Mental Diseases', Lausanne, Switzerland., Xin L; Animal Imaging and Technology Core (AIT), Center for Biomedical Imaging (CIBM), Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland., Fournier M; Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital (CHUV), Lausanne, Switzerland.; National Center of Competence in Research (NCCR) 'SYNAPSY - The Synaptic Bases of Mental Diseases', Lausanne, Switzerland., Griffa A; Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland.; Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands., Cleusix M; Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital (CHUV), Lausanne, Switzerland.; National Center of Competence in Research (NCCR) 'SYNAPSY - The Synaptic Bases of Mental Diseases', Lausanne, Switzerland., Jenni R; Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital (CHUV), Lausanne, Switzerland.; National Center of Competence in Research (NCCR) 'SYNAPSY - The Synaptic Bases of Mental Diseases', Lausanne, Switzerland., Cuenod M; Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital (CHUV), Lausanne, Switzerland., Gruetter R; Animal Imaging and Technology Core (AIT), Center for Biomedical Imaging (CIBM), Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.; Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland., Hagmann P; National Center of Competence in Research (NCCR) 'SYNAPSY - The Synaptic Bases of Mental Diseases', Lausanne, Switzerland.; Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland., Conus P; Service of General Psychiatry, Department of Psychiatry, Lausanne University Hospital (CHUV), Lausanne, Switzerland.; National Center of Competence in Research (NCCR) 'SYNAPSY - The Synaptic Bases of Mental Diseases', Lausanne, Switzerland., Baumann PS; Service of General Psychiatry, Department of Psychiatry, Lausanne University Hospital (CHUV), Lausanne, Switzerland.; Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital (CHUV), Lausanne, Switzerland.; National Center of Competence in Research (NCCR) 'SYNAPSY - The Synaptic Bases of Mental Diseases', Lausanne, Switzerland., Do KQ; Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital (CHUV), Lausanne, Switzerland. Kim.Do@CHUV.ch.; National Center of Competence in Research (NCCR) 'SYNAPSY - The Synaptic Bases of Mental Diseases', Lausanne, Switzerland. Kim.Do@CHUV.ch.
Source: Translational psychiatry [Transl Psychiatry] 2018 Oct 12; Vol. 8 (1), pp. 220. Date of Electronic Publication: 2018 Oct 12.
Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: N-acetylcysteine add-on treatment leads to an improvement of fornix white matter integrity in early psychosis: a double-blind randomized placebo-controlled trial.
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  Data: <searchLink fieldCode="AU" term="%22Klauser+P%22">Klauser P</searchLink>; Service of General Psychiatry, Department of Psychiatry, Lausanne University Hospital (CHUV), Lausanne, Switzerland.; Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital (CHUV), Lausanne, Switzerland.; National Center of Competence in Research (NCCR) 'SYNAPSY - The Synaptic Bases of Mental Diseases', Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Xin+L%22">Xin L</searchLink>; Animal Imaging and Technology Core (AIT), Center for Biomedical Imaging (CIBM), Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Fournier+M%22">Fournier M</searchLink>; Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital (CHUV), Lausanne, Switzerland.; National Center of Competence in Research (NCCR) 'SYNAPSY - The Synaptic Bases of Mental Diseases', Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Griffa+A%22">Griffa A</searchLink>; Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland.; Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Cleusix+M%22">Cleusix M</searchLink>; Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital (CHUV), Lausanne, Switzerland.; National Center of Competence in Research (NCCR) 'SYNAPSY - The Synaptic Bases of Mental Diseases', Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Jenni+R%22">Jenni R</searchLink>; Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital (CHUV), Lausanne, Switzerland.; National Center of Competence in Research (NCCR) 'SYNAPSY - The Synaptic Bases of Mental Diseases', Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Cuenod+M%22">Cuenod M</searchLink>; Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital (CHUV), Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Gruetter+R%22">Gruetter R</searchLink>; Animal Imaging and Technology Core (AIT), Center for Biomedical Imaging (CIBM), Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.; Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hagmann+P%22">Hagmann P</searchLink>; National Center of Competence in Research (NCCR) 'SYNAPSY - The Synaptic Bases of Mental Diseases', Lausanne, Switzerland.; Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Conus+P%22">Conus P</searchLink>; Service of General Psychiatry, Department of Psychiatry, Lausanne University Hospital (CHUV), Lausanne, Switzerland.; National Center of Competence in Research (NCCR) 'SYNAPSY - The Synaptic Bases of Mental Diseases', Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Baumann+PS%22">Baumann PS</searchLink>; Service of General Psychiatry, Department of Psychiatry, Lausanne University Hospital (CHUV), Lausanne, Switzerland.; Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital (CHUV), Lausanne, Switzerland.; National Center of Competence in Research (NCCR) 'SYNAPSY - The Synaptic Bases of Mental Diseases', Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Do+KQ%22">Do KQ</searchLink>; Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital (CHUV), Lausanne, Switzerland. Kim.Do@CHUV.ch.; National Center of Competence in Research (NCCR) 'SYNAPSY - The Synaptic Bases of Mental Diseases', Lausanne, Switzerland. Kim.Do@CHUV.ch.
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