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Somatic Gene Editing of GUCY2D by AAV-CRISPR/Cas9 Alters Retinal Structure and Function in Mouse and Macaque.

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Title: Somatic Gene Editing of GUCY2D by AAV-CRISPR/Cas9 Alters Retinal Structure and Function in Mouse and Macaque.
Authors: McCullough KT; 1 Department of Ophthalmology, University of Florida, Gainesville, Florida., Boye SL; 1 Department of Ophthalmology, University of Florida, Gainesville, Florida., Fajardo D; 1 Department of Ophthalmology, University of Florida, Gainesville, Florida., Calabro K; 1 Department of Ophthalmology, University of Florida, Gainesville, Florida., Peterson JJ; 1 Department of Ophthalmology, University of Florida, Gainesville, Florida., Strang CE; 2 Department of Ophthalmology, University of Alabama at Birmingham, Birmingham, Alabama., Chakraborty D; 2 Department of Ophthalmology, University of Alabama at Birmingham, Birmingham, Alabama., Gloskowski S; 3 Editas Medicine, Cambridge, Massachusetts., Haskett S; 3 Editas Medicine, Cambridge, Massachusetts., Samuelsson S; 3 Editas Medicine, Cambridge, Massachusetts., Jiang H; 3 Editas Medicine, Cambridge, Massachusetts., Witherspoon CD; 2 Department of Ophthalmology, University of Alabama at Birmingham, Birmingham, Alabama., Gamlin PD; 2 Department of Ophthalmology, University of Alabama at Birmingham, Birmingham, Alabama., Maeder ML; 3 Editas Medicine, Cambridge, Massachusetts., Boye SE; 1 Department of Ophthalmology, University of Florida, Gainesville, Florida.
Source: Human gene therapy [Hum Gene Ther] 2019 May; Vol. 30 (5), pp. 571-589. Date of Electronic Publication: 2018 Dec 20.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: M.A. Liebert Country of Publication: United States NLM ID: 9008950 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7422 (Electronic) Linking ISSN: 10430342 NLM ISO Abbreviation: Hum Gene Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Somatic Gene Editing of GUCY2D by AAV-CRISPR/Cas9 Alters Retinal Structure and Function in Mouse and Macaque.
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  Data: <searchLink fieldCode="AU" term="%22McCullough+KT%22">McCullough KT</searchLink>; 1 Department of Ophthalmology, University of Florida, Gainesville, Florida.<br /><searchLink fieldCode="AU" term="%22Boye+SL%22">Boye SL</searchLink>; 1 Department of Ophthalmology, University of Florida, Gainesville, Florida.<br /><searchLink fieldCode="AU" term="%22Fajardo+D%22">Fajardo D</searchLink>; 1 Department of Ophthalmology, University of Florida, Gainesville, Florida.<br /><searchLink fieldCode="AU" term="%22Calabro+K%22">Calabro K</searchLink>; 1 Department of Ophthalmology, University of Florida, Gainesville, Florida.<br /><searchLink fieldCode="AU" term="%22Peterson+JJ%22">Peterson JJ</searchLink>; 1 Department of Ophthalmology, University of Florida, Gainesville, Florida.<br /><searchLink fieldCode="AU" term="%22Strang+CE%22">Strang CE</searchLink>; 2 Department of Ophthalmology, University of Alabama at Birmingham, Birmingham, Alabama.<br /><searchLink fieldCode="AU" term="%22Chakraborty+D%22">Chakraborty D</searchLink>; 2 Department of Ophthalmology, University of Alabama at Birmingham, Birmingham, Alabama.<br /><searchLink fieldCode="AU" term="%22Gloskowski+S%22">Gloskowski S</searchLink>; 3 Editas Medicine, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Haskett+S%22">Haskett S</searchLink>; 3 Editas Medicine, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Samuelsson+S%22">Samuelsson S</searchLink>; 3 Editas Medicine, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Jiang+H%22">Jiang H</searchLink>; 3 Editas Medicine, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Witherspoon+CD%22">Witherspoon CD</searchLink>; 2 Department of Ophthalmology, University of Alabama at Birmingham, Birmingham, Alabama.<br /><searchLink fieldCode="AU" term="%22Gamlin+PD%22">Gamlin PD</searchLink>; 2 Department of Ophthalmology, University of Alabama at Birmingham, Birmingham, Alabama.<br /><searchLink fieldCode="AU" term="%22Maeder+ML%22">Maeder ML</searchLink>; 3 Editas Medicine, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Boye+SE%22">Boye SE</searchLink>; 1 Department of Ophthalmology, University of Florida, Gainesville, Florida.
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  Data: <searchLink fieldCode="JN" term="%229008950%22">Human gene therapy</searchLink> [Hum Gene Ther] 2019 May; Vol. 30 (5), pp. 571-589. <i>Date of Electronic Publication: </i>2018 Dec 20.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22M%2EA%2E+Liebert%22">M.A. Liebert </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9008950 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1557-7422 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210430342%22">10430342 </searchLink><i>NLM ISO Abbreviation: </i>Hum Gene Ther <i>Subsets: </i>MEDLINE
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        Value: 10.1089/hum.2018.193
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