View in EDS HTML Full Text PDF Full Text

Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration.

Saved in:
Bibliographic Details
Title: Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration.
Authors: McFarland JM; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA., Ho ZV; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA., Kugener G; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA., Dempster JM; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA., Montgomery PG; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA., Bryan JG; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA., Krill-Burger JM; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA., Green TM; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA., Vazquez F; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA.; Dana-Farber Cancer Institute, Boston, 02215, MA, USA., Boehm JS; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA., Golub TR; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA.; Dana-Farber Cancer Institute, Boston, 02215, MA, USA.; Harvard Medical School, Boston, 02115, MA, USA.; Boston Children's Hospital, Boston, 02115, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, 20815, MD, USA., Hahn WC; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA.; Dana-Farber Cancer Institute, Boston, 02215, MA, USA.; Harvard Medical School, Boston, 02115, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, 02115, MA, USA., Root DE; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA., Tsherniak A; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA. aviad@broadinstitute.org.
Source: Nature communications [Nat Commun] 2018 Nov 02; Vol. 9 (1), pp. 4610. Date of Electronic Publication: 2018 Nov 02.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 30389920
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22McFarland+JM%22">McFarland JM</searchLink>; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ho+ZV%22">Ho ZV</searchLink>; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kugener+G%22">Kugener G</searchLink>; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA.<br /><searchLink fieldCode="AU" term="%22Dempster+JM%22">Dempster JM</searchLink>; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA.<br /><searchLink fieldCode="AU" term="%22Montgomery+PG%22">Montgomery PG</searchLink>; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bryan+JG%22">Bryan JG</searchLink>; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA.<br /><searchLink fieldCode="AU" term="%22Krill-Burger+JM%22">Krill-Burger JM</searchLink>; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA.<br /><searchLink fieldCode="AU" term="%22Green+TM%22">Green TM</searchLink>; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA.<br /><searchLink fieldCode="AU" term="%22Vazquez+F%22">Vazquez F</searchLink>; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA.; Dana-Farber Cancer Institute, Boston, 02215, MA, USA.<br /><searchLink fieldCode="AU" term="%22Boehm+JS%22">Boehm JS</searchLink>; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA.<br /><searchLink fieldCode="AU" term="%22Golub+TR%22">Golub TR</searchLink>; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA.; Dana-Farber Cancer Institute, Boston, 02215, MA, USA.; Harvard Medical School, Boston, 02115, MA, USA.; Boston Children's Hospital, Boston, 02115, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, 20815, MD, USA.<br /><searchLink fieldCode="AU" term="%22Hahn+WC%22">Hahn WC</searchLink>; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA.; Dana-Farber Cancer Institute, Boston, 02215, MA, USA.; Harvard Medical School, Boston, 02115, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, 02115, MA, USA.<br /><searchLink fieldCode="AU" term="%22Root+DE%22">Root DE</searchLink>; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA.<br /><searchLink fieldCode="AU" term="%22Tsherniak+A%22">Tsherniak A</searchLink>; Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA. aviad@broadinstitute.org.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2018 Nov 02; Vol. 9 (1), pp. 4610. <i>Date of Electronic Publication: </i>2018 Nov 02.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=30389920
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41467-018-06916-5
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 4610
    Titles:
      – TitleFull: Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: McFarland JM
      – PersonEntity:
          Name:
            NameFull: Ho ZV
      – PersonEntity:
          Name:
            NameFull: Kugener G
      – PersonEntity:
          Name:
            NameFull: Dempster JM
      – PersonEntity:
          Name:
            NameFull: Montgomery PG
      – PersonEntity:
          Name:
            NameFull: Bryan JG
      – PersonEntity:
          Name:
            NameFull: Krill-Burger JM
      – PersonEntity:
          Name:
            NameFull: Green TM
      – PersonEntity:
          Name:
            NameFull: Vazquez F
      – PersonEntity:
          Name:
            NameFull: Boehm JS
      – PersonEntity:
          Name:
            NameFull: Golub TR
      – PersonEntity:
          Name:
            NameFull: Hahn WC
      – PersonEntity:
          Name:
            NameFull: Root DE
      – PersonEntity:
          Name:
            NameFull: Tsherniak A
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 02
              M: 11
              Text: 2018 Nov 02
              Type: published
              Y: 2018
          Identifiers:
            – Type: issn-electronic
              Value: 2041-1723
          Numbering:
            – Type: volume
              Value: 9
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Nature communications
              Type: main
ResultId 1