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An RORγt Oral Inhibitor Modulates IL-17 Responses in Peripheral Blood and Intestinal Mucosa of Crohn's Disease Patients.

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Title: An RORγt Oral Inhibitor Modulates IL-17 Responses in Peripheral Blood and Intestinal Mucosa of Crohn's Disease Patients.
Authors: Bassolas-Molina H; Department of Gastroenterology, IDIBAPS, Hospital Clínic, CIBERehd, Barcelona, Spain., Raymond E; Department of Immunology and Respiratory, Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT, United States., Labadia M; Department of Immunology and Respiratory, Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT, United States., Wahle J; Department of Immunology and Respiratory, Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT, United States., Ferrer-Picón E; Department of Gastroenterology, IDIBAPS, Hospital Clínic, CIBERehd, Barcelona, Spain., Panzenbeck M; Department of Immunology and Respiratory, Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT, United States., Zheng J; Department of Immunology and Respiratory, Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT, United States., Harcken C; Department of Immunology and Respiratory, Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT, United States., Hughes R; Department of Small Molecule Discovery Research, Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT, United States., Turner M; Department of Small Molecule Discovery Research, Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT, United States., Smith D; Department of Small Molecule Discovery Research, Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT, United States., Calderón-Gómez E; Department of Gastroenterology, IDIBAPS, Hospital Clínic, CIBERehd, Barcelona, Spain., Esteller M; Department of Gastroenterology, IDIBAPS, Hospital Clínic, CIBERehd, Barcelona, Spain., Carrasco A; Department of Gastroenterology, Hospital Universitari Mutua Terrassa, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain., Esteve M; Department of Gastroenterology, Hospital Universitari Mutua Terrassa, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain., Dotti I; Department of Gastroenterology, IDIBAPS, Hospital Clínic, CIBERehd, Barcelona, Spain., Corraliza AM; Department of Gastroenterology, IDIBAPS, Hospital Clínic, CIBERehd, Barcelona, Spain., Masamunt MC; Department of Gastroenterology, IDIBAPS, Hospital Clínic, CIBERehd, Barcelona, Spain., Arajol C; Department of Gastroenterology, Hospital Universitari de Bellvitge-IDIBELL, Barcelona, Spain., Guardiola J; Department of Gastroenterology, Hospital Universitari de Bellvitge-IDIBELL, Barcelona, Spain., Ricart E; Department of Gastroenterology, IDIBAPS, Hospital Clínic, CIBERehd, Barcelona, Spain., Nabozny G; Department of Immunology and Respiratory, Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT, United States., Salas A; Department of Gastroenterology, IDIBAPS, Hospital Clínic, CIBERehd, Barcelona, Spain.
Source: Frontiers in immunology [Front Immunol] 2018 Oct 22; Vol. 9, pp. 2307. Date of Electronic Publication: 2018 Oct 22 (Print Publication: 2018).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: An RORγt Oral Inhibitor Modulates IL-17 Responses in Peripheral Blood and Intestinal Mucosa of Crohn's Disease Patients.
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