HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design.

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Bibliographic Details
Title: HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design.
Authors: Flyak AI; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA., Ruiz S; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA., Colbert MD; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Luong T; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA., Crowe JE Jr; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Bailey JR; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Electronic address: jbailey7@jhmi.edu., Bjorkman PJ; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA. Electronic address: bjorkman@caltech.edu.
Source: Cell host & microbe [Cell Host Microbe] 2018 Nov 14; Vol. 24 (5), pp. 703-716.e3.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101302316 Publication Model: Print Cited Medium: Internet ISSN: 1934-6069 (Electronic) Linking ISSN: 19313128 NLM ISO Abbreviation: Cell Host Microbe Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1934-6069
DOI:10.1016/j.chom.2018.10.009