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PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer.

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Title: PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer.
Authors: Rebecca VW; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Nicastri MC; Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania., Fennelly C; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Chude CI; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Barber-Rotenberg JS; Department of Biochemistry and Biophysics, Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania., Ronghe A; Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Wistar Institute, Philadelphia, Pennsylvania., McAfee Q; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., McLaughlin NP; Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania., Zhang G; Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Wistar Institute, Philadelphia, Pennsylvania., Goldman AR; Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Wistar Institute, Philadelphia, Pennsylvania., Ojha R; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Piao S; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Noguera-Ortega E; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Martorella A; Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Wistar Institute, Philadelphia, Pennsylvania., Alicea GM; Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Wistar Institute, Philadelphia, Pennsylvania., Lee JJ; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Schuchter LM; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Xu X; Department of Pathology, University of Pennsylvania, Philadelphia, Pennsylvania., Herlyn M; Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Wistar Institute, Philadelphia, Pennsylvania., Marmorstein R; Department of Biochemistry and Biophysics, Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania., Gimotty PA; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania., Speicher DW; Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Wistar Institute, Philadelphia, Pennsylvania., Winkler JD; Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania. Winkler@sas.upenn.edu Ravi.amaravadi@uphs.upenn.edu., Amaravadi RK; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Winkler@sas.upenn.edu Ravi.amaravadi@uphs.upenn.edu.
Source: Cancer discovery [Cancer Discov] 2019 Feb; Vol. 9 (2), pp. 220-229. Date of Electronic Publication: 2018 Nov 15.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer.
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  Data: <searchLink fieldCode="AU" term="%22Rebecca+VW%22">Rebecca VW</searchLink>; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Nicastri+MC%22">Nicastri MC</searchLink>; Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Fennelly+C%22">Fennelly C</searchLink>; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Chude+CI%22">Chude CI</searchLink>; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Barber-Rotenberg+JS%22">Barber-Rotenberg JS</searchLink>; Department of Biochemistry and Biophysics, Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Ronghe+A%22">Ronghe A</searchLink>; Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Wistar Institute, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22McAfee+Q%22">McAfee Q</searchLink>; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22McLaughlin+NP%22">McLaughlin NP</searchLink>; Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Zhang+G%22">Zhang G</searchLink>; Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Wistar Institute, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Goldman+AR%22">Goldman AR</searchLink>; Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Wistar Institute, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Ojha+R%22">Ojha R</searchLink>; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Piao+S%22">Piao S</searchLink>; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Noguera-Ortega+E%22">Noguera-Ortega E</searchLink>; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Martorella+A%22">Martorella A</searchLink>; Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Wistar Institute, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Alicea+GM%22">Alicea GM</searchLink>; Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Wistar Institute, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Lee+JJ%22">Lee JJ</searchLink>; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Schuchter+LM%22">Schuchter LM</searchLink>; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Xu+X%22">Xu X</searchLink>; Department of Pathology, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Herlyn+M%22">Herlyn M</searchLink>; Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Wistar Institute, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Marmorstein+R%22">Marmorstein R</searchLink>; Department of Biochemistry and Biophysics, Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Gimotty+PA%22">Gimotty PA</searchLink>; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Speicher+DW%22">Speicher DW</searchLink>; Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Wistar Institute, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Winkler+JD%22">Winkler JD</searchLink>; Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania. Winkler@sas.upenn.edu Ravi.amaravadi@uphs.upenn.edu.<br /><searchLink fieldCode="AU" term="%22Amaravadi+RK%22">Amaravadi RK</searchLink>; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Winkler@sas.upenn.edu Ravi.amaravadi@uphs.upenn.edu.
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  Data: <searchLink fieldCode="JN" term="%22101561693%22">Cancer discovery</searchLink> [Cancer Discov] 2019 Feb; Vol. 9 (2), pp. 220-229. <i>Date of Electronic Publication: </i>2018 Nov 15.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101561693 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2159-8290 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221598274%22">21598274 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Discov <i>Subsets: </i>MEDLINE
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        Value: 10.1158/2159-8290.CD-18-0706
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              Text: 2019 Feb
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