TPT sulfonate, a single, oral dose schistosomicidal prodrug: In vivo efficacy, disposition and metabolic profiling.
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| Title: | TPT sulfonate, a single, oral dose schistosomicidal prodrug: In vivo efficacy, disposition and metabolic profiling. |
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| Authors: | Wolfe AR; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, 533 Parnassus Ave, San Francisco, CA, 94143, USA; Center for Discovery and Innovation in Parasitic Diseases, University of California, 1700 4th St, San Francisco, CA, 94158, USA., Neitz RJ; Center for Discovery and Innovation in Parasitic Diseases, University of California, 1700 4th St, San Francisco, CA, 94158, USA; Department of Pharmaceutical Chemistry, University of California, 1700 4th St, San Francisco, CA, 94158, USA., Burlingame M; Department of Pharmaceutical Chemistry, University of California, 1700 4th St, San Francisco, CA, 94158, USA., Suzuki BM; Center for Discovery and Innovation in Parasitic Diseases, University of California, 1700 4th St, San Francisco, CA, 94158, USA; Department of Pathology, University of California, 1700 4th St, San Francisco, CA, 94158, USA., Lim KC; Center for Discovery and Innovation in Parasitic Diseases, University of California, 1700 4th St, San Francisco, CA, 94158, USA; Department of Pathology, University of California, 1700 4th St, San Francisco, CA, 94158, USA., Scheideler M; Human First Therapeutics LLC, 9600 Dewitt Drive, Ste 1, Silver Spring, MD, 20910, USA., Nelson DL; Pro-Rectory of Research and Graduate Study, Federal University of the Valleys of Jequitinhonha and Mucuri, 39100-000, Diamantina, MG, Brazil., Benet LZ; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, 533 Parnassus Ave, San Francisco, CA, 94143, USA; Center for Discovery and Innovation in Parasitic Diseases, University of California, 1700 4th St, San Francisco, CA, 94158, USA., Caffrey CR; Center for Discovery and Innovation in Parasitic Diseases, University of California, 1700 4th St, San Francisco, CA, 94158, USA; Department of Pathology, University of California, 1700 4th St, San Francisco, CA, 94158, USA. Electronic address: ccaffrey@ucsd.edu. |
| Source: | International journal for parasitology. Drugs and drug resistance [Int J Parasitol Drugs Drug Resist] 2018 Dec; Vol. 8 (3), pp. 571-586. Date of Electronic Publication: 2018 Nov 20. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101576715 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-3207 (Electronic) Linking ISSN: 22113207 NLM ISO Abbreviation: Int J Parasitol Drugs Drug Resist Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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