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The lysyl oxidase like 2/3 enzymatic inhibitor, PXS-5153A, reduces crosslinks and ameliorates fibrosis.

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Title: The lysyl oxidase like 2/3 enzymatic inhibitor, PXS-5153A, reduces crosslinks and ameliorates fibrosis.
Authors: Schilter H; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia., Findlay AD; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia., Perryman L; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia., Yow TT; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia., Moses J; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia., Zahoor A; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia., Turner CI; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia., Deodhar M; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia., Foot JS; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia., Zhou W; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia., Greco A; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia., Joshi A; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia., Rayner B; Heart Research Institute, Sydney, NSW, Australia.; Sydney Medical School, University of Sydney, Sydney, NSW, Australia., Townsend S; Centre for Liver Research, Institute of Immunology, National Institute for Health Research Liver Biomedical Research Unit, University Hospitals, Birmingham, UK.; Birmingham NHS Foundation Trust, University of Birmingham, Birmingham, UK., Buson A; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia., Jarolimek W; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia.
Source: Journal of cellular and molecular medicine [J Cell Mol Med] 2019 Mar; Vol. 23 (3), pp. 1759-1770. Date of Electronic Publication: 2018 Dec 09.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101083777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1582-4934 (Electronic) Linking ISSN: 15821838 NLM ISO Abbreviation: J Cell Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The lysyl oxidase like 2/3 enzymatic inhibitor, PXS-5153A, reduces crosslinks and ameliorates fibrosis.
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  Data: <searchLink fieldCode="AU" term="%22Schilter+H%22">Schilter H</searchLink>; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Findlay+AD%22">Findlay AD</searchLink>; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Perryman+L%22">Perryman L</searchLink>; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Yow+TT%22">Yow TT</searchLink>; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Moses+J%22">Moses J</searchLink>; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Zahoor+A%22">Zahoor A</searchLink>; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Turner+CI%22">Turner CI</searchLink>; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Deodhar+M%22">Deodhar M</searchLink>; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Foot+JS%22">Foot JS</searchLink>; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Zhou+W%22">Zhou W</searchLink>; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Greco+A%22">Greco A</searchLink>; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Joshi+A%22">Joshi A</searchLink>; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Rayner+B%22">Rayner B</searchLink>; Heart Research Institute, Sydney, NSW, Australia.; Sydney Medical School, University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Townsend+S%22">Townsend S</searchLink>; Centre for Liver Research, Institute of Immunology, National Institute for Health Research Liver Biomedical Research Unit, University Hospitals, Birmingham, UK.; Birmingham NHS Foundation Trust, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Buson+A%22">Buson A</searchLink>; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Jarolimek+W%22">Jarolimek W</searchLink>; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia.
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  Data: <searchLink fieldCode="JN" term="%22101083777%22">Journal of cellular and molecular medicine</searchLink> [J Cell Mol Med] 2019 Mar; Vol. 23 (3), pp. 1759-1770. <i>Date of Electronic Publication: </i>2018 Dec 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Blackwell%22">Wiley-Blackwell </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101083777 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1582-4934 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215821838%22">15821838 </searchLink><i>NLM ISO Abbreviation: </i>J Cell Mol Med <i>Subsets: </i>MEDLINE
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        Value: 10.1111/jcmm.14074
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        Text: English
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        StartPage: 1759
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              Text: 2019 Mar
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