The lysyl oxidase like 2/3 enzymatic inhibitor, PXS-5153A, reduces crosslinks and ameliorates fibrosis.
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| Title: | The lysyl oxidase like 2/3 enzymatic inhibitor, PXS-5153A, reduces crosslinks and ameliorates fibrosis. |
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| Authors: | Schilter H; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia., Findlay AD; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia., Perryman L; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia., Yow TT; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia., Moses J; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia., Zahoor A; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia., Turner CI; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia., Deodhar M; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia., Foot JS; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia., Zhou W; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia., Greco A; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia., Joshi A; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia., Rayner B; Heart Research Institute, Sydney, NSW, Australia.; Sydney Medical School, University of Sydney, Sydney, NSW, Australia., Townsend S; Centre for Liver Research, Institute of Immunology, National Institute for Health Research Liver Biomedical Research Unit, University Hospitals, Birmingham, UK.; Birmingham NHS Foundation Trust, University of Birmingham, Birmingham, UK., Buson A; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia., Jarolimek W; Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia. |
| Source: | Journal of cellular and molecular medicine [J Cell Mol Med] 2019 Mar; Vol. 23 (3), pp. 1759-1770. Date of Electronic Publication: 2018 Dec 09. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101083777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1582-4934 (Electronic) Linking ISSN: 15821838 NLM ISO Abbreviation: J Cell Mol Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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