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SOX9 regulated matrix proteins are increased in patients serum and correlate with severity of liver fibrosis.

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Title: SOX9 regulated matrix proteins are increased in patients serum and correlate with severity of liver fibrosis.
Authors: Athwal VS; Wellcome Centre for Cell-Matrix Research, Faculty of Biology, Medicine & Health, Manchester Academic Health Science Centre, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.; Division of Diabetes, Endocrinology and Gastroenterology, Faculty of Biology, Medicine & Health, University of Manchester, Manchester Academic Health Science Centre, Oxford Road, Manchester, UK.; Research & Innovation Division, Central Manchester University Hospitals NHS Foundation Trust, Oxford Road, Manchester, M13 9PT, UK., Pritchett J; Wellcome Centre for Cell-Matrix Research, Faculty of Biology, Medicine & Health, Manchester Academic Health Science Centre, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.; Division of Diabetes, Endocrinology and Gastroenterology, Faculty of Biology, Medicine & Health, University of Manchester, Manchester Academic Health Science Centre, Oxford Road, Manchester, UK.; School of Healthcare Science, Manchester Metropolitan University, Manchester, M1 5GD, UK., Martin K; Wellcome Centre for Cell-Matrix Research, Faculty of Biology, Medicine & Health, Manchester Academic Health Science Centre, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.; Division of Diabetes, Endocrinology and Gastroenterology, Faculty of Biology, Medicine & Health, University of Manchester, Manchester Academic Health Science Centre, Oxford Road, Manchester, UK.; Research & Innovation Division, Central Manchester University Hospitals NHS Foundation Trust, Oxford Road, Manchester, M13 9PT, UK., Llewellyn J; Division of Diabetes, Endocrinology and Gastroenterology, Faculty of Biology, Medicine & Health, University of Manchester, Manchester Academic Health Science Centre, Oxford Road, Manchester, UK., Scott J; Wellcome Centre for Cell-Matrix Research, Faculty of Biology, Medicine & Health, Manchester Academic Health Science Centre, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.; Division of Diabetes, Endocrinology and Gastroenterology, Faculty of Biology, Medicine & Health, University of Manchester, Manchester Academic Health Science Centre, Oxford Road, Manchester, UK.; Research & Innovation Division, Central Manchester University Hospitals NHS Foundation Trust, Oxford Road, Manchester, M13 9PT, UK., Harvey E; Division of Diabetes, Endocrinology and Gastroenterology, Faculty of Biology, Medicine & Health, University of Manchester, Manchester Academic Health Science Centre, Oxford Road, Manchester, UK., Zaitoun AM; Department of Cellular Pathology, NIHR Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, UK., Mullan AF; Wellcome Centre for Cell-Matrix Research, Faculty of Biology, Medicine & Health, Manchester Academic Health Science Centre, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.; Division of Diabetes, Endocrinology and Gastroenterology, Faculty of Biology, Medicine & Health, University of Manchester, Manchester Academic Health Science Centre, Oxford Road, Manchester, UK.; Research & Innovation Division, Central Manchester University Hospitals NHS Foundation Trust, Oxford Road, Manchester, M13 9PT, UK., Zeef LAH; Bioinformatics Core Facility, Faculty of Life Sciences, University of Manchester, Manchester, UK., Friedman SL; Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY10029, USA., Irving WL; NIHR Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, UK.; School of Life Sciences, NIHR Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, UK., Hanley NA; Division of Diabetes, Endocrinology and Gastroenterology, Faculty of Biology, Medicine & Health, University of Manchester, Manchester Academic Health Science Centre, Oxford Road, Manchester, UK.; Research & Innovation Division, Central Manchester University Hospitals NHS Foundation Trust, Oxford Road, Manchester, M13 9PT, UK., Guha IN; NIHR Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, UK., Piper Hanley K; Wellcome Centre for Cell-Matrix Research, Faculty of Biology, Medicine & Health, Manchester Academic Health Science Centre, University of Manchester, Oxford Road, Manchester, M13 9PT, UK. karen.piperhanley@manchester.ac.uk.; Division of Diabetes, Endocrinology and Gastroenterology, Faculty of Biology, Medicine & Health, University of Manchester, Manchester Academic Health Science Centre, Oxford Road, Manchester, UK. karen.piperhanley@manchester.ac.uk.; Research & Innovation Division, Central Manchester University Hospitals NHS Foundation Trust, Oxford Road, Manchester, M13 9PT, UK. karen.piperhanley@manchester.ac.uk.
Source: Scientific reports [Sci Rep] 2018 Dec 17; Vol. 8 (1), pp. 17905. Date of Electronic Publication: 2018 Dec 17.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2045-2322
DOI:10.1038/s41598-018-36037-4