Sulfonylated Benzothiazoles as Inhibitors of Endothelial Lipase.
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| Title: | Sulfonylated Benzothiazoles as Inhibitors of Endothelial Lipase. |
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| Authors: | Johnson JA; Departments of Discovery Chemistry, Biology, Pharmaceutics, Mechanistic Biochemistry, Preclinical Candidate Optimization, Bioanalytical Research, and Crystallography, Bristol-Myers Squibb, Research and Development, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States., Tora G; Departments of Discovery Chemistry, Biology, Pharmaceutics, Mechanistic Biochemistry, Preclinical Candidate Optimization, Bioanalytical Research, and Crystallography, Bristol-Myers Squibb, Research and Development, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States., Pi Z; Departments of Discovery Chemistry, Biology, Pharmaceutics, Mechanistic Biochemistry, Preclinical Candidate Optimization, Bioanalytical Research, and Crystallography, Bristol-Myers Squibb, Research and Development, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States., Phillips M; Departments of Discovery Chemistry, Biology, Pharmaceutics, Mechanistic Biochemistry, Preclinical Candidate Optimization, Bioanalytical Research, and Crystallography, Bristol-Myers Squibb, Research and Development, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States., Yin X; Departments of Discovery Chemistry, Biology, Pharmaceutics, Mechanistic Biochemistry, Preclinical Candidate Optimization, Bioanalytical Research, and Crystallography, Bristol-Myers Squibb, Research and Development, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States., Yang R; Departments of Discovery Chemistry, Biology, Pharmaceutics, Mechanistic Biochemistry, Preclinical Candidate Optimization, Bioanalytical Research, and Crystallography, Bristol-Myers Squibb, Research and Development, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States., Zhao L; Departments of Discovery Chemistry, Biology, Pharmaceutics, Mechanistic Biochemistry, Preclinical Candidate Optimization, Bioanalytical Research, and Crystallography, Bristol-Myers Squibb, Research and Development, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States., Chen AY; Departments of Discovery Chemistry, Biology, Pharmaceutics, Mechanistic Biochemistry, Preclinical Candidate Optimization, Bioanalytical Research, and Crystallography, Bristol-Myers Squibb, Research and Development, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States., Taylor DS; Departments of Discovery Chemistry, Biology, Pharmaceutics, Mechanistic Biochemistry, Preclinical Candidate Optimization, Bioanalytical Research, and Crystallography, Bristol-Myers Squibb, Research and Development, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States., Basso M; Departments of Discovery Chemistry, Biology, Pharmaceutics, Mechanistic Biochemistry, Preclinical Candidate Optimization, Bioanalytical Research, and Crystallography, Bristol-Myers Squibb, Research and Development, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States., Rose A; Departments of Discovery Chemistry, Biology, Pharmaceutics, Mechanistic Biochemistry, Preclinical Candidate Optimization, Bioanalytical Research, and Crystallography, Bristol-Myers Squibb, Research and Development, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States., Behnia K; Departments of Discovery Chemistry, Biology, Pharmaceutics, Mechanistic Biochemistry, Preclinical Candidate Optimization, Bioanalytical Research, and Crystallography, Bristol-Myers Squibb, Research and Development, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States., Onorato J; Departments of Discovery Chemistry, Biology, Pharmaceutics, Mechanistic Biochemistry, Preclinical Candidate Optimization, Bioanalytical Research, and Crystallography, Bristol-Myers Squibb, Research and Development, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States., Chen XQ; Departments of Discovery Chemistry, Biology, Pharmaceutics, Mechanistic Biochemistry, Preclinical Candidate Optimization, Bioanalytical Research, and Crystallography, Bristol-Myers Squibb, Research and Development, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States., Abell LM; Departments of Discovery Chemistry, Biology, Pharmaceutics, Mechanistic Biochemistry, Preclinical Candidate Optimization, Bioanalytical Research, and Crystallography, Bristol-Myers Squibb, Research and Development, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States., Lu H; Departments of Discovery Chemistry, Biology, Pharmaceutics, Mechanistic Biochemistry, Preclinical Candidate Optimization, Bioanalytical Research, and Crystallography, Bristol-Myers Squibb, Research and Development, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States., Locke G; Departments of Discovery Chemistry, Biology, Pharmaceutics, Mechanistic Biochemistry, Preclinical Candidate Optimization, Bioanalytical Research, and Crystallography, Bristol-Myers Squibb, Research and Development, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States., Caporuscio C; Departments of Discovery Chemistry, Biology, Pharmaceutics, Mechanistic Biochemistry, Preclinical Candidate Optimization, Bioanalytical Research, and Crystallography, Bristol-Myers Squibb, Research and Development, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States., Galella M; Departments of Discovery Chemistry, Biology, Pharmaceutics, Mechanistic Biochemistry, Preclinical Candidate Optimization, Bioanalytical Research, and Crystallography, Bristol-Myers Squibb, Research and Development, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States., Adam LP; Departments of Discovery Chemistry, Biology, Pharmaceutics, Mechanistic Biochemistry, Preclinical Candidate Optimization, Bioanalytical Research, and Crystallography, Bristol-Myers Squibb, Research and Development, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States., Gordon D; Departments of Discovery Chemistry, Biology, Pharmaceutics, Mechanistic Biochemistry, Preclinical Candidate Optimization, Bioanalytical Research, and Crystallography, Bristol-Myers Squibb, Research and Development, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States., Wexler RR; Departments of Discovery Chemistry, Biology, Pharmaceutics, Mechanistic Biochemistry, Preclinical Candidate Optimization, Bioanalytical Research, and Crystallography, Bristol-Myers Squibb, Research and Development, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States., Finlay HJ; Departments of Discovery Chemistry, Biology, Pharmaceutics, Mechanistic Biochemistry, Preclinical Candidate Optimization, Bioanalytical Research, and Crystallography, Bristol-Myers Squibb, Research and Development, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States. |
| Source: | ACS medicinal chemistry letters [ACS Med Chem Lett] 2018 Nov 21; Vol. 9 (12), pp. 1263-1268. Date of Electronic Publication: 2018 Nov 21 (Print Publication: 2018). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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