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Mesyl phosphoramidate antisense oligonucleotides as an alternative to phosphorothioates with improved biochemical and biological properties.

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Title: Mesyl phosphoramidate antisense oligonucleotides as an alternative to phosphorothioates with improved biochemical and biological properties.
Authors: Miroshnichenko SK; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences (ICBFM SB RAS), 630090 Novosibirsk, Russia., Patutina OA; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences (ICBFM SB RAS), 630090 Novosibirsk, Russia., Burakova EA; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences (ICBFM SB RAS), 630090 Novosibirsk, Russia., Chelobanov BP; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences (ICBFM SB RAS), 630090 Novosibirsk, Russia., Fokina AA; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences (ICBFM SB RAS), 630090 Novosibirsk, Russia., Vlassov VV; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences (ICBFM SB RAS), 630090 Novosibirsk, Russia., Altman S; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06520; sidney.altman@yale.edu dast@niboch.nsc.ru.; Life Sciences, Arizona State University, Tempe, AZ 85287., Zenkova MA; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences (ICBFM SB RAS), 630090 Novosibirsk, Russia., Stetsenko DA; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences (ICBFM SB RAS), 630090 Novosibirsk, Russia; sidney.altman@yale.edu dast@niboch.nsc.ru.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Jan 22; Vol. 116 (4), pp. 1229-1234. Date of Electronic Publication: 2019 Jan 08.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Mesyl phosphoramidate antisense oligonucleotides as an alternative to phosphorothioates with improved biochemical and biological properties.
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  Data: <searchLink fieldCode="AU" term="%22Miroshnichenko+SK%22">Miroshnichenko SK</searchLink>; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences (ICBFM SB RAS), 630090 Novosibirsk, Russia.<br /><searchLink fieldCode="AU" term="%22Patutina+OA%22">Patutina OA</searchLink>; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences (ICBFM SB RAS), 630090 Novosibirsk, Russia.<br /><searchLink fieldCode="AU" term="%22Burakova+EA%22">Burakova EA</searchLink>; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences (ICBFM SB RAS), 630090 Novosibirsk, Russia.<br /><searchLink fieldCode="AU" term="%22Chelobanov+BP%22">Chelobanov BP</searchLink>; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences (ICBFM SB RAS), 630090 Novosibirsk, Russia.<br /><searchLink fieldCode="AU" term="%22Fokina+AA%22">Fokina AA</searchLink>; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences (ICBFM SB RAS), 630090 Novosibirsk, Russia.<br /><searchLink fieldCode="AU" term="%22Vlassov+VV%22">Vlassov VV</searchLink>; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences (ICBFM SB RAS), 630090 Novosibirsk, Russia.<br /><searchLink fieldCode="AU" term="%22Altman+S%22">Altman S</searchLink>; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06520; sidney.altman@yale.edu dast@niboch.nsc.ru.; Life Sciences, Arizona State University, Tempe, AZ 85287.<br /><searchLink fieldCode="AU" term="%22Zenkova+MA%22">Zenkova MA</searchLink>; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences (ICBFM SB RAS), 630090 Novosibirsk, Russia.<br /><searchLink fieldCode="AU" term="%22Stetsenko+DA%22">Stetsenko DA</searchLink>; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences (ICBFM SB RAS), 630090 Novosibirsk, Russia; sidney.altman@yale.edu dast@niboch.nsc.ru.
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  Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2019 Jan 22; Vol. 116 (4), pp. 1229-1234. <i>Date of Electronic Publication: </i>2019 Jan 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22National+Academy+of+Sciences%22">National Academy of Sciences </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7505876 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1091-6490 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200278424%22">00278424 </searchLink><i>NLM ISO Abbreviation: </i>Proc Natl Acad Sci U S A <i>Subsets: </i>MEDLINE
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        Value: 10.1073/pnas.1813376116
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              Text: 2019 Jan 22
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