Open-label study to evaluate trifluridine/tipiracil safety, tolerability and pharmacokinetics in patients with advanced solid tumours and hepatic impairment.
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| Title: | Open-label study to evaluate trifluridine/tipiracil safety, tolerability and pharmacokinetics in patients with advanced solid tumours and hepatic impairment. |
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| Authors: | Saif MW; Northwell Health Cancer Institute, Lake Success, NY, USA., Rosen L; University of California, Los Angeles, CA, USA., Rudek MA; Johns Hopkins University, Baltimore, MD, USA., Sun W; University of Kansas, Kansas City, KS, USA., Shepard DR; Cleveland Clinic, Cleveland, OH, USA., Becerra C; Texas Oncology, Baylor University Medical Center, Dallas, TX, USA., Yamashita F; Taiho Oncology, Inc, Princeton, NJ, USA., Bebeau P; Taiho Oncology, Inc, Princeton, NJ, USA., Winkler R; Taiho Oncology, Inc, Princeton, NJ, USA. |
| Source: | British journal of clinical pharmacology [Br J Clin Pharmacol] 2019 Jun; Vol. 85 (6), pp. 1239-1246. Date of Electronic Publication: 2019 Mar 28. |
| Publication Type: | Clinical Trial, Phase I; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1365-2125 |
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| DOI: | 10.1111/bcp.13856 |
