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Discovery of a ZIP7 inhibitor from a Notch pathway screen.

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Title: Discovery of a ZIP7 inhibitor from a Notch pathway screen.
Authors: Nolin E; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Gans S; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Llamas L; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Bandyopadhyay S; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Brittain SM; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Bernasconi-Elias P; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Carter KP; Department of Chemistry and Biochemistry and BioFrontiers Institute, University of Colorado, Boulder, CO, USA., Loureiro JJ; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Thomas JR; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Schirle M; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Yang Y; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Guo N; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Roma G; Novartis Institutes for Biomedical Research, Basel, Switzerland., Schuierer S; Novartis Institutes for Biomedical Research, Basel, Switzerland., Beibel M; Novartis Institutes for Biomedical Research, Basel, Switzerland., Lindeman A; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Sigoillot F; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Chen A; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Xie KX; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Ho S; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Reece-Hoyes J; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Weihofen WA; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Tyskiewicz K; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Hoepfner D; Novartis Institutes for Biomedical Research, Basel, Switzerland., McDonald RI; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Guthrie N; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Dogra A; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Guo H; Novartis Institutes for Biomedical Research, Shanghai, China., Shao J; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Ding J; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Canham SM; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Boynton G; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., George EL; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Kang ZB; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Antczak C; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Porter JA; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Wallace O; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Tallarico JA; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Palmer AE; Department of Chemistry and Biochemistry and BioFrontiers Institute, University of Colorado, Boulder, CO, USA., Jenkins JL; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Jain RK; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Bushell SM; Novartis Institutes for Biomedical Research, Cambridge, MA, USA. simon.bushell@novartis.com., Fryer CJ; Novartis Institutes for Biomedical Research, Cambridge, MA, USA. christy.fryer@novartis.com.
Source: Nature chemical biology [Nat Chem Biol] 2019 Feb; Vol. 15 (2), pp. 179-188. Date of Electronic Publication: 2019 Jan 14.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Discovery of a ZIP7 inhibitor from a Notch pathway screen.
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  Data: <searchLink fieldCode="AU" term="%22Nolin+E%22">Nolin E</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Gans+S%22">Gans S</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Llamas+L%22">Llamas L</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bandyopadhyay+S%22">Bandyopadhyay S</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Brittain+SM%22">Brittain SM</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bernasconi-Elias+P%22">Bernasconi-Elias P</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Carter+KP%22">Carter KP</searchLink>; Department of Chemistry and Biochemistry and BioFrontiers Institute, University of Colorado, Boulder, CO, USA.<br /><searchLink fieldCode="AU" term="%22Loureiro+JJ%22">Loureiro JJ</searchLink>; 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Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sigoillot+F%22">Sigoillot F</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Chen+A%22">Chen A</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Xie+KX%22">Xie KX</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ho+S%22">Ho S</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Reece-Hoyes+J%22">Reece-Hoyes J</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Weihofen+WA%22">Weihofen WA</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Tyskiewicz+K%22">Tyskiewicz K</searchLink>; 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Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Boynton+G%22">Boynton G</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22George+EL%22">George EL</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kang+ZB%22">Kang ZB</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Antczak+C%22">Antczak C</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Porter+JA%22">Porter JA</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Wallace+O%22">Wallace O</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Tallarico+JA%22">Tallarico JA</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Palmer+AE%22">Palmer AE</searchLink>; Department of Chemistry and Biochemistry and BioFrontiers Institute, University of Colorado, Boulder, CO, USA.<br /><searchLink fieldCode="AU" term="%22Jenkins+JL%22">Jenkins JL</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Jain+RK%22">Jain RK</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bushell+SM%22">Bushell SM</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA. simon.bushell@novartis.com.<br /><searchLink fieldCode="AU" term="%22Fryer+CJ%22">Fryer CJ</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA. christy.fryer@novartis.com.
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  Data: <searchLink fieldCode="JN" term="%22101231976%22">Nature chemical biology</searchLink> [Nat Chem Biol] 2019 Feb; Vol. 15 (2), pp. 179-188. <i>Date of Electronic Publication: </i>2019 Jan 14.
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