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Targeting of cathepsin S reduces cystic fibrosis-like lung disease.

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Title: Targeting of cathepsin S reduces cystic fibrosis-like lung disease.
Authors: Small DM; Airway Innate Immunity Research (AiiR) Group, Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.; These two authors contributed equally to this work., Brown RR; Airway Innate Immunity Research (AiiR) Group, Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.; These two authors contributed equally to this work., Doherty DF; Airway Innate Immunity Research (AiiR) Group, Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK., Abladey A; Airway Innate Immunity Research (AiiR) Group, Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK., Zhou-Suckow Z; Dept of Translational Pulmonology, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), University of Heidelberg, Heidelberg, Germany., Delaney RJ; Airway Innate Immunity Research (AiiR) Group, Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK., Kerrigan L; Airway Innate Immunity Research (AiiR) Group, Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK., Dougan CM; Airway Innate Immunity Research (AiiR) Group, Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK., Borensztajn KS; INSERM UMRS_933, Université Pierre et Marie Curie, Hôpital Trousseau, Paris, France., Holsinger L; ViroBay Inc., Menlo Park, CA, USA., Booth R; ViroBay Inc., Menlo Park, CA, USA., Scott CJ; Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, UK., López-Campos G; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK., Elborn JS; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.; Respiratory Medicine, Imperial College and Royal Brompton Hospital, London, UK., Mall MA; Dept of Translational Pulmonology, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), University of Heidelberg, Heidelberg, Germany.; Dept of Pediatric Pulmonology and Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany.; Berlin Institute of Health (BIH), Berlin, Germany., Weldon S; Airway Innate Immunity Research (AiiR) Group, Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK., Taggart CC; Airway Innate Immunity Research (AiiR) Group, Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.
Source: The European respiratory journal [Eur Respir J] 2019 Mar 28; Vol. 53 (3). Date of Electronic Publication: 2019 Mar 28 (Print Publication: 2019).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: European Respiratory Society Country of Publication: England NLM ID: 8803460 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1399-3003 (Electronic) Linking ISSN: 09031936 NLM ISO Abbreviation: Eur Respir J Subsets: MEDLINE
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  Data: Targeting of cathepsin S reduces cystic fibrosis-like lung disease.
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  Data: <searchLink fieldCode="AU" term="%22Small+DM%22">Small DM</searchLink>; Airway Innate Immunity Research (AiiR) Group, Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.; These two authors contributed equally to this work.<br /><searchLink fieldCode="AU" term="%22Brown+RR%22">Brown RR</searchLink>; Airway Innate Immunity Research (AiiR) Group, Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.; These two authors contributed equally to this work.<br /><searchLink fieldCode="AU" term="%22Doherty+DF%22">Doherty DF</searchLink>; Airway Innate Immunity Research (AiiR) Group, Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Abladey+A%22">Abladey A</searchLink>; Airway Innate Immunity Research (AiiR) Group, Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Zhou-Suckow+Z%22">Zhou-Suckow Z</searchLink>; Dept of Translational Pulmonology, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Delaney+RJ%22">Delaney RJ</searchLink>; Airway Innate Immunity Research (AiiR) Group, Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Kerrigan+L%22">Kerrigan L</searchLink>; Airway Innate Immunity Research (AiiR) Group, Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Dougan+CM%22">Dougan CM</searchLink>; Airway Innate Immunity Research (AiiR) Group, Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Borensztajn+KS%22">Borensztajn KS</searchLink>; INSERM UMRS_933, Université Pierre et Marie Curie, Hôpital Trousseau, Paris, France.<br /><searchLink fieldCode="AU" term="%22Holsinger+L%22">Holsinger L</searchLink>; ViroBay Inc., Menlo Park, CA, USA.<br /><searchLink fieldCode="AU" term="%22Booth+R%22">Booth R</searchLink>; ViroBay Inc., Menlo Park, CA, USA.<br /><searchLink fieldCode="AU" term="%22Scott+CJ%22">Scott CJ</searchLink>; Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22López-Campos+G%22">López-Campos G</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Elborn+JS%22">Elborn JS</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.; Respiratory Medicine, Imperial College and Royal Brompton Hospital, London, UK.<br /><searchLink fieldCode="AU" term="%22Mall+MA%22">Mall MA</searchLink>; Dept of Translational Pulmonology, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), University of Heidelberg, Heidelberg, Germany.; Dept of Pediatric Pulmonology and Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany.; Berlin Institute of Health (BIH), Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Weldon+S%22">Weldon S</searchLink>; Airway Innate Immunity Research (AiiR) Group, Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Taggart+CC%22">Taggart CC</searchLink>; Airway Innate Immunity Research (AiiR) Group, Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.
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  Data: <searchLink fieldCode="JN" term="%228803460%22">The European respiratory journal</searchLink> [Eur Respir J] 2019 Mar 28; Vol. 53 (3). <i>Date of Electronic Publication: </i>2019 Mar 28 (<i>Print Publication: </i>2019).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22European+Respiratory+Society%22">European Respiratory Society </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8803460 <i>Publication Model: </i>Electronic-Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1399-3003 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209031936%22">09031936 </searchLink><i>NLM ISO Abbreviation: </i>Eur Respir J <i>Subsets: </i>MEDLINE
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