The lineage stability and suppressive program of regulatory T cells require protein O-GlcNAcylation.

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Title: The lineage stability and suppressive program of regulatory T cells require protein O-GlcNAcylation.
Authors: Liu B; Department of Integrative Biology and Physiology, University of Minnesota, Minneapolis, MN, 55455, USA., Salgado OC; Center for Immunology, University of Minnesota, Minneapolis, MN, 55455, USA., Singh S; Division of Blood and Marrow Transplantation, Cancer Center and the Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, 55455, USA., Hippen KL; Division of Blood and Marrow Transplantation, Cancer Center and the Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, 55455, USA., Maynard JC; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA, 94158, USA., Burlingame AL; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA, 94158, USA., Ball LE; Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, Charleston, SC, 29425, USA., Blazar BR; Division of Blood and Marrow Transplantation, Cancer Center and the Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, 55455, USA., Farrar MA; Center for Immunology, University of Minnesota, Minneapolis, MN, 55455, USA.; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, 55455, USA., Hogquist KA; Center for Immunology, University of Minnesota, Minneapolis, MN, 55455, USA. hogqu001@umn.edu.; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, 55455, USA. hogqu001@umn.edu., Ruan HB; Department of Integrative Biology and Physiology, University of Minnesota, Minneapolis, MN, 55455, USA. hruan@umn.edu.; Center for Immunology, University of Minnesota, Minneapolis, MN, 55455, USA. hruan@umn.edu.
Source: Nature communications [Nat Commun] 2019 Jan 21; Vol. 10 (1), pp. 354. Date of Electronic Publication: 2019 Jan 21.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-019-08300-3