The phenylketonuria-associated substitution R68S converts phenylalanine hydroxylase to a constitutively active enzyme but reduces its stability.
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| Title: | The phenylketonuria-associated substitution R68S converts phenylalanine hydroxylase to a constitutively active enzyme but reduces its stability. |
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| Authors: | Khan CA; From the Department of Biochemistry and Structural Biology, UT Health San Antonio, San Antonio, Texas 78229 and., Meisburger SP; the Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853., Ando N; the Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853., Fitzpatrick PF; From the Department of Biochemistry and Structural Biology, UT Health San Antonio, San Antonio, Texas 78229 and fitzpatrickp@uthscsa.edu. |
| Source: | The Journal of biological chemistry [J Biol Chem] 2019 Mar 22; Vol. 294 (12), pp. 4359-4367. Date of Electronic Publication: 2019 Jan 23. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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