Graft-implanted, enzyme responsive, tacrolimus-eluting hydrogel enables long-term survival of orthotopic porcine limb vascularized composite allografts: A proof of concept study.
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| Title: | Graft-implanted, enzyme responsive, tacrolimus-eluting hydrogel enables long-term survival of orthotopic porcine limb vascularized composite allografts: A proof of concept study. |
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| Authors: | Fries CA; United States Army Institute of Surgical Research, San Antonio, TX, United States of America.; Royal Centre for Defence Medicine, ICT Centre, Birmingham, United Kingdom., Lawson SD; United States Army Institute of Surgical Research, San Antonio, TX, United States of America., Wang LC; United States Army Institute of Surgical Research, San Antonio, TX, United States of America., Slaughter KV; Center for Nanomedicine and Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, United States of America., Vemula PK; Institute for Stem Cell Biology and Regenerative Medicine (inStem), UAS-GKVK Campus, Bangalore, India., Dhayani A; Institute for Stem Cell Biology and Regenerative Medicine (inStem), UAS-GKVK Campus, Bangalore, India.; The School of Chemical and Biotechnology, SASTRA University, Thanjavur, India., Joshi N; Center for Nanomedicine and Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, United States of America.; Harvard Medical School, Boston, MA, United States of America., Karp JM; Center for Nanomedicine and Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, United States of America.; Harvard Medical School, Boston, MA, United States of America., Rickard RF; Royal Centre for Defence Medicine, ICT Centre, Birmingham, United Kingdom., Gorantla VS; Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston Salem, NC, United States of America.; RESTOR Program, 59th MDW/ Science and Technology, Joint Base San Antonio, TX, United States of America., Davis MR; United States Army Institute of Surgical Research, San Antonio, TX, United States of America.; RESTOR Program, 59th MDW/ Science and Technology, Joint Base San Antonio, TX, United States of America. |
| Source: | PloS one [PLoS One] 2019 Jan 24; Vol. 14 (1), pp. e0210914. Date of Electronic Publication: 2019 Jan 24 (Print Publication: 2019). |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1932-6203 |
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| DOI: | 10.1371/journal.pone.0210914 |
