Graft-implanted, enzyme responsive, tacrolimus-eluting hydrogel enables long-term survival of orthotopic porcine limb vascularized composite allografts: A proof of concept study.

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Title: Graft-implanted, enzyme responsive, tacrolimus-eluting hydrogel enables long-term survival of orthotopic porcine limb vascularized composite allografts: A proof of concept study.
Authors: Fries CA; United States Army Institute of Surgical Research, San Antonio, TX, United States of America.; Royal Centre for Defence Medicine, ICT Centre, Birmingham, United Kingdom., Lawson SD; United States Army Institute of Surgical Research, San Antonio, TX, United States of America., Wang LC; United States Army Institute of Surgical Research, San Antonio, TX, United States of America., Slaughter KV; Center for Nanomedicine and Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, United States of America., Vemula PK; Institute for Stem Cell Biology and Regenerative Medicine (inStem), UAS-GKVK Campus, Bangalore, India., Dhayani A; Institute for Stem Cell Biology and Regenerative Medicine (inStem), UAS-GKVK Campus, Bangalore, India.; The School of Chemical and Biotechnology, SASTRA University, Thanjavur, India., Joshi N; Center for Nanomedicine and Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, United States of America.; Harvard Medical School, Boston, MA, United States of America., Karp JM; Center for Nanomedicine and Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, United States of America.; Harvard Medical School, Boston, MA, United States of America., Rickard RF; Royal Centre for Defence Medicine, ICT Centre, Birmingham, United Kingdom., Gorantla VS; Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston Salem, NC, United States of America.; RESTOR Program, 59th MDW/ Science and Technology, Joint Base San Antonio, TX, United States of America., Davis MR; United States Army Institute of Surgical Research, San Antonio, TX, United States of America.; RESTOR Program, 59th MDW/ Science and Technology, Joint Base San Antonio, TX, United States of America.
Source: PloS one [PLoS One] 2019 Jan 24; Vol. 14 (1), pp. e0210914. Date of Electronic Publication: 2019 Jan 24 (Print Publication: 2019).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Graft-implanted, enzyme responsive, tacrolimus-eluting hydrogel enables long-term survival of orthotopic porcine limb vascularized composite allografts: A proof of concept study.
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  Data: <searchLink fieldCode="AU" term="%22Fries+CA%22">Fries CA</searchLink>; United States Army Institute of Surgical Research, San Antonio, TX, United States of America.; Royal Centre for Defence Medicine, ICT Centre, Birmingham, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Lawson+SD%22">Lawson SD</searchLink>; United States Army Institute of Surgical Research, San Antonio, TX, United States of America.<br /><searchLink fieldCode="AU" term="%22Wang+LC%22">Wang LC</searchLink>; United States Army Institute of Surgical Research, San Antonio, TX, United States of America.<br /><searchLink fieldCode="AU" term="%22Slaughter+KV%22">Slaughter KV</searchLink>; Center for Nanomedicine and Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Vemula+PK%22">Vemula PK</searchLink>; Institute for Stem Cell Biology and Regenerative Medicine (inStem), UAS-GKVK Campus, Bangalore, India.<br /><searchLink fieldCode="AU" term="%22Dhayani+A%22">Dhayani A</searchLink>; Institute for Stem Cell Biology and Regenerative Medicine (inStem), UAS-GKVK Campus, Bangalore, India.; The School of Chemical and Biotechnology, SASTRA University, Thanjavur, India.<br /><searchLink fieldCode="AU" term="%22Joshi+N%22">Joshi N</searchLink>; Center for Nanomedicine and Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, United States of America.; Harvard Medical School, Boston, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Karp+JM%22">Karp JM</searchLink>; Center for Nanomedicine and Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, United States of America.; Harvard Medical School, Boston, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Rickard+RF%22">Rickard RF</searchLink>; Royal Centre for Defence Medicine, ICT Centre, Birmingham, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gorantla+VS%22">Gorantla VS</searchLink>; Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston Salem, NC, United States of America.; RESTOR Program, 59th MDW/ Science and Technology, Joint Base San Antonio, TX, United States of America.<br /><searchLink fieldCode="AU" term="%22Davis+MR%22">Davis MR</searchLink>; United States Army Institute of Surgical Research, San Antonio, TX, United States of America.; RESTOR Program, 59th MDW/ Science and Technology, Joint Base San Antonio, TX, United States of America.
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  Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2019 Jan 24; Vol. 14 (1), pp. e0210914. <i>Date of Electronic Publication: </i>2019 Jan 24 (<i>Print Publication: </i>2019).
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