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Alzheimer's disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph.

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Title: Alzheimer's disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph.
Authors: Magno L; UCL Alzheimer's Research UK, Drug Discovery Institute, London, UK. l.magno@ucl.ac.uk., Lessard CB; Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease, and McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA., Martins M; Research Department of Structural and Molecular Biology, University College London, London, UK.; Present address: Instituto de Medicina Molecular - João Lobo Antunes, Faculdade de Medicina de Lisboa, Lisbon, Portugal., Lang V; UCL Alzheimer's Research UK, Drug Discovery Institute, London, UK., Cruz P; Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease, and McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA., Asi Y; Department of Neurodegenerative Diseases, UCL Queen Square Institute of Neurology, University College London, London, UK.; Queen Square Brain Bank for Neurological Disorders, Department of Movement Disorders, UCL Queen Square Institute of Neurology, University College London, London, UK., Katan M; Research Department of Structural and Molecular Biology, University College London, London, UK., Bilsland J; UCL Alzheimer's Research UK, Drug Discovery Institute, London, UK., Lashley T; Department of Neurodegenerative Diseases, UCL Queen Square Institute of Neurology, University College London, London, UK.; Queen Square Brain Bank for Neurological Disorders, Department of Movement Disorders, UCL Queen Square Institute of Neurology, University College London, London, UK., Chakrabarty P; Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease, and McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA., Golde TE; Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease, and McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA., Whiting PJ; UCL Alzheimer's Research UK, Drug Discovery Institute, London, UK. p.whiting@ucl.ac.uk.; Dementia Research Institute, UCL, London, UK. p.whiting@ucl.ac.uk.
Source: Alzheimer's research & therapy [Alzheimers Res Ther] 2019 Feb 02; Vol. 11 (1), pp. 16. Date of Electronic Publication: 2019 Feb 02.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN: 1758-9193 (Electronic) NLM ISO Abbreviation: Alzheimers Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Alzheimer's disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph.
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  Data: <searchLink fieldCode="AU" term="%22Magno+L%22">Magno L</searchLink>; UCL Alzheimer's Research UK, Drug Discovery Institute, London, UK. l.magno@ucl.ac.uk.<br /><searchLink fieldCode="AU" term="%22Lessard+CB%22">Lessard CB</searchLink>; Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease, and McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Martins+M%22">Martins M</searchLink>; Research Department of Structural and Molecular Biology, University College London, London, UK.; Present address: Instituto de Medicina Molecular - João Lobo Antunes, Faculdade de Medicina de Lisboa, Lisbon, Portugal.<br /><searchLink fieldCode="AU" term="%22Lang+V%22">Lang V</searchLink>; UCL Alzheimer's Research UK, Drug Discovery Institute, London, UK.<br /><searchLink fieldCode="AU" term="%22Cruz+P%22">Cruz P</searchLink>; Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease, and McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Asi+Y%22">Asi Y</searchLink>; Department of Neurodegenerative Diseases, UCL Queen Square Institute of Neurology, University College London, London, UK.; Queen Square Brain Bank for Neurological Disorders, Department of Movement Disorders, UCL Queen Square Institute of Neurology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Katan+M%22">Katan M</searchLink>; Research Department of Structural and Molecular Biology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Bilsland+J%22">Bilsland J</searchLink>; UCL Alzheimer's Research UK, Drug Discovery Institute, London, UK.<br /><searchLink fieldCode="AU" term="%22Lashley+T%22">Lashley T</searchLink>; Department of Neurodegenerative Diseases, UCL Queen Square Institute of Neurology, University College London, London, UK.; Queen Square Brain Bank for Neurological Disorders, Department of Movement Disorders, UCL Queen Square Institute of Neurology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Chakrabarty+P%22">Chakrabarty P</searchLink>; Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease, and McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Golde+TE%22">Golde TE</searchLink>; Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease, and McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Whiting+PJ%22">Whiting PJ</searchLink>; UCL Alzheimer's Research UK, Drug Discovery Institute, London, UK. p.whiting@ucl.ac.uk.; Dementia Research Institute, UCL, London, UK. p.whiting@ucl.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%22101511643%22">Alzheimer's research & therapy</searchLink> [Alzheimers Res Ther] 2019 Feb 02; Vol. 11 (1), pp. 16. <i>Date of Electronic Publication: </i>2019 Feb 02.
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