Toward Second-Generation Cardiomyogenic and Anti-cardiofibrotic 1,4-Dihydropyridine-Class TGFβ Inhibitors.
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| Title: | Toward Second-Generation Cardiomyogenic and Anti-cardiofibrotic 1,4-Dihydropyridine-Class TGFβ Inhibitors. |
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| Authors: | Längle D; Department of Chemistry and Chemical Biology, Technische Universität Dortmund, Otto-Hahn-Str. 4, 44227, Dortmund, Germany.; Department of Pharmaceutical and Medicinal Chemistry, Christian-Albrechts-Universität Kiel, Gutenbergstr. 76, 24118, Kiel, Germany., Werner TR; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany., Wesseler F; Department of Chemistry and Chemical Biology, Technische Universität Dortmund, Otto-Hahn-Str. 4, 44227, Dortmund, Germany., Reckzeh E; Department of Chemistry and Chemical Biology, Technische Universität Dortmund, Otto-Hahn-Str. 4, 44227, Dortmund, Germany., Schaumann N; Department of Chemistry and Chemical Biology, Technische Universität Dortmund, Otto-Hahn-Str. 4, 44227, Dortmund, Germany., Drowley L; Cardiovascular, Renal and Metabolic Diseases IMED Biotech Unit, AstraZeneca Gothenburg, Pepparsleden 1, 43 183, Mölndal, Sweden., Polla M; Cardiovascular, Renal and Metabolic Diseases IMED Biotech Unit, AstraZeneca Gothenburg, Pepparsleden 1, 43 183, Mölndal, Sweden., Plowright AT; Cardiovascular, Renal and Metabolic Diseases IMED Biotech Unit, AstraZeneca Gothenburg, Pepparsleden 1, 43 183, Mölndal, Sweden., Hirt MN; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany., Eschenhagen T; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany., Schade D; Department of Chemistry and Chemical Biology, Technische Universität Dortmund, Otto-Hahn-Str. 4, 44227, Dortmund, Germany.; Department of Pharmaceutical and Medicinal Chemistry, Christian-Albrechts-Universität Kiel, Gutenbergstr. 76, 24118, Kiel, Germany. |
| Source: | ChemMedChem [ChemMedChem] 2019 Apr 17; Vol. 14 (8), pp. 810-822. Date of Electronic Publication: 2019 Feb 28. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1860-7187 |
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| DOI: | 10.1002/cmdc.201900036 |
