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Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity.

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Title: Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity.
Authors: Lin KH; Department of Pharmacology & Cancer Biology, Duke University School of Medicine, Durham, NC, USA., Xie A; Department of Pharmacology & Cancer Biology, Duke University School of Medicine, Durham, NC, USA., Rutter JC; Department of Pharmacology & Cancer Biology, Duke University School of Medicine, Durham, NC, USA., Ahn YR; Department of Pharmacology & Cancer Biology, Duke University School of Medicine, Durham, NC, USA., Lloyd-Cowden JM; Department of Medicine, Duke University Medical Center, Durham, NC, USA., Nichols AG; Department of Pediatrics, Duke University Medical Center, Durham, NC, USA., Soderquist RS; Department of Pharmacology & Cancer Biology, Duke University School of Medicine, Durham, NC, USA., Koves TR; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA., Muoio DM; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA., MacIver NJ; Department of Pharmacology & Cancer Biology, Duke University School of Medicine, Durham, NC, USA; Department of Pediatrics, Duke University Medical Center, Durham, NC, USA., Lamba JK; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA., Pardee TS; Department of Internal Medicine, Section on Hematology and Oncology, Wake Forest Baptist Health, Winston-Salem, NC, USA., McCall CM; Department of Pathology, Duke University Medical Center, Durham, NC, USA., Rizzieri DA; Department of Medicine, Duke University Medical Center, Durham, NC, USA., Wood KC; Department of Pharmacology & Cancer Biology, Duke University School of Medicine, Durham, NC, USA. Electronic address: kris.wood@duke.edu.
Source: Cell metabolism [Cell Metab] 2019 May 07; Vol. 29 (5), pp. 1217-1231.e7. Date of Electronic Publication: 2019 Feb 14.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101233170 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-7420 (Electronic) Linking ISSN: 15504131 NLM ISO Abbreviation: Cell Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity.
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  Data: <searchLink fieldCode="AU" term="%22Lin+KH%22">Lin KH</searchLink>; Department of Pharmacology & Cancer Biology, Duke University School of Medicine, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Xie+A%22">Xie A</searchLink>; Department of Pharmacology & Cancer Biology, Duke University School of Medicine, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Rutter+JC%22">Rutter JC</searchLink>; Department of Pharmacology & Cancer Biology, Duke University School of Medicine, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Ahn+YR%22">Ahn YR</searchLink>; Department of Pharmacology & Cancer Biology, Duke University School of Medicine, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Lloyd-Cowden+JM%22">Lloyd-Cowden JM</searchLink>; Department of Medicine, Duke University Medical Center, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Nichols+AG%22">Nichols AG</searchLink>; Department of Pediatrics, Duke University Medical Center, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Soderquist+RS%22">Soderquist RS</searchLink>; Department of Pharmacology & Cancer Biology, Duke University School of Medicine, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Koves+TR%22">Koves TR</searchLink>; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Muoio+DM%22">Muoio DM</searchLink>; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22MacIver+NJ%22">MacIver NJ</searchLink>; Department of Pharmacology & Cancer Biology, Duke University School of Medicine, Durham, NC, USA; Department of Pediatrics, Duke University Medical Center, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Lamba+JK%22">Lamba JK</searchLink>; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Pardee+TS%22">Pardee TS</searchLink>; Department of Internal Medicine, Section on Hematology and Oncology, Wake Forest Baptist Health, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22McCall+CM%22">McCall CM</searchLink>; Department of Pathology, Duke University Medical Center, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Rizzieri+DA%22">Rizzieri DA</searchLink>; Department of Medicine, Duke University Medical Center, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Wood+KC%22">Wood KC</searchLink>; Department of Pharmacology & Cancer Biology, Duke University School of Medicine, Durham, NC, USA. Electronic address: kris.wood@duke.edu.
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  Data: <searchLink fieldCode="JN" term="%22101233170%22">Cell metabolism</searchLink> [Cell Metab] 2019 May 07; Vol. 29 (5), pp. 1217-1231.e7. <i>Date of Electronic Publication: </i>2019 Feb 14.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101233170 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1932-7420 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215504131%22">15504131 </searchLink><i>NLM ISO Abbreviation: </i>Cell Metab <i>Subsets: </i>MEDLINE
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              Text: 2019 May 07
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