HIV-1 vaccination by needle-free oral injection induces strong mucosal immunity and protects against SHIV challenge.
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| Title: | HIV-1 vaccination by needle-free oral injection induces strong mucosal immunity and protects against SHIV challenge. |
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| Authors: | Jones AT; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA, 30329, USA.; Department of Microbiology and Immunology, Emory School of Medicine, Emory University, Atlanta, Georgia, 30329, USA., Shen X; Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC, 27710, USA., Walter KL; Department of Microbiology, Immunology and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA, 70112, USA., LaBranche CC; Department of Surgery, Duke University Medical Center, Durham, NC, 27710, USA., Wyatt LS; Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Tomaras GD; Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC, 27710, USA., Montefiori DC; Department of Surgery, Duke University Medical Center, Durham, NC, 27710, USA., Moss B; Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Barouch DH; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02115, USA., Clements JD; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA, 8638, USA., Kozlowski PA; Department of Microbiology, Immunology and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA, 70112, USA., Varadarajan R; Molecular Biophysics Unit, Indian Institute of Science, Bangalore, 560012, India., Amara RR; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA, 30329, USA. ramara@emory.edu.; Department of Microbiology and Immunology, Emory School of Medicine, Emory University, Atlanta, Georgia, 30329, USA. ramara@emory.edu. |
| Source: | Nature communications [Nat Commun] 2019 Feb 18; Vol. 10 (1), pp. 798. Date of Electronic Publication: 2019 Feb 18. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-019-08739-4 |
