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Multicentre randomised controlled trial to investigate usefulness of the rapid diagnostic βLACTA test performed directly on bacterial cell pellets from respiratory, urinary or blood samples for the early de-escalation of carbapenems in septic intensive care unit patients: the BLUE-CarbA protocol.

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Title: Multicentre randomised controlled trial to investigate usefulness of the rapid diagnostic βLACTA test performed directly on bacterial cell pellets from respiratory, urinary or blood samples for the early de-escalation of carbapenems in septic intensive care unit patients: the BLUE-CarbA protocol.
Authors: Garnier M; Anesthesiology and Intensive Care Medicine Department, APHP-Tenon University Hospital, Paris, France.; Medico-surgical Intensive Care Unit, APHP-Tenon University Hospital, Paris, France.; Paris 6 School of Medicine, Sorbonne University, Paris, France., Gallah S; APHP-GHUEP-Microbiology Department, Paris, France., Vimont S; Paris 6 School of Medicine, Sorbonne University, Paris, France.; APHP-GHUEP-Microbiology Department, Paris, France., Benzerara Y; APHP-GHUEP-Microbiology Department, Paris, France., Labbe V; Medico-surgical Intensive Care Unit, APHP-Tenon University Hospital, Paris, France., Constant AL; Cardio-thoracic Surgical Intensive Care Unit, APHP-European Georges Pompidou University Hospital, Paris, France., Siami S; Polyvalent Intensive Care Unit, Sud Essonne Hospital, Etampes, France., Guerot E; APHP-European Georges Pompidou University Hospital, Medical Intensive Care Unit, Paris, France., Compain F; Microbiology Department, APHP-European Georges Pompidou University Hospital, Paris, France., Mainardi JL; Microbiology Department, APHP-European Georges Pompidou University Hospital, Paris, France., Montil M; APHP-Clinical Research Platform (URCEst-CRCEst-CRB), St Antoine Hospital, Paris, France., Quesnel C; Anesthesiology and Intensive Care Medicine Department, APHP-Tenon University Hospital, Paris, France.; Paris 6 School of Medicine, Sorbonne University, Paris, France.
Corporate Authors: BLUE-CarbA study group.
Source: BMJ open [BMJ Open] 2019 Feb 19; Vol. 9 (2), pp. e024561. Date of Electronic Publication: 2019 Feb 19.
Publication Type: Clinical Trial Protocol; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2044-6055
DOI:10.1136/bmjopen-2018-024561