Targeting the Sigma-1 Receptor via Pridopidine Ameliorates Central Features of ALS Pathology in a SOD1G93A Model.

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Title: Targeting the Sigma-1 Receptor via Pridopidine Ameliorates Central Features of ALS Pathology in a SOD1G93A Model.
Authors: Ionescu A; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel., Gradus T; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel., Altman T; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel., Maimon R; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel., Saraf Avraham N; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel., Geva M; Teva Pharmaceuticals Ltd, Petah Tikva, Israel.; Prilenia Therapeutics, Herzliya, Israel., Hayden M; Teva Pharmaceuticals Ltd, Petah Tikva, Israel.; Prilenia Therapeutics, Herzliya, Israel., Perlson E; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel. eranpe@tauex.tau.ac.il.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel. eranpe@tauex.tau.ac.il.
Source: Cell death & disease [Cell Death Dis] 2019 Mar 01; Vol. 10 (3), pp. 210. Date of Electronic Publication: 2019 Mar 01.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting the Sigma-1 Receptor via Pridopidine Ameliorates Central Features of ALS Pathology in a SOD1<superscript>G93A</superscript> Model.
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  Data: <searchLink fieldCode="AU" term="%22Ionescu+A%22">Ionescu A</searchLink>; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel.<br /><searchLink fieldCode="AU" term="%22Gradus+T%22">Gradus T</searchLink>; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel.<br /><searchLink fieldCode="AU" term="%22Altman+T%22">Altman T</searchLink>; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel.<br /><searchLink fieldCode="AU" term="%22Maimon+R%22">Maimon R</searchLink>; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel.<br /><searchLink fieldCode="AU" term="%22Saraf+Avraham+N%22">Saraf Avraham N</searchLink>; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel.<br /><searchLink fieldCode="AU" term="%22Geva+M%22">Geva M</searchLink>; Teva Pharmaceuticals Ltd, Petah Tikva, Israel.; Prilenia Therapeutics, Herzliya, Israel.<br /><searchLink fieldCode="AU" term="%22Hayden+M%22">Hayden M</searchLink>; Teva Pharmaceuticals Ltd, Petah Tikva, Israel.; Prilenia Therapeutics, Herzliya, Israel.<br /><searchLink fieldCode="AU" term="%22Perlson+E%22">Perlson E</searchLink>; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel. eranpe@tauex.tau.ac.il.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel. eranpe@tauex.tau.ac.il.
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  Data: <searchLink fieldCode="JN" term="%22101524092%22">Cell death & disease</searchLink> [Cell Death Dis] 2019 Mar 01; Vol. 10 (3), pp. 210. <i>Date of Electronic Publication: </i>2019 Mar 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101524092 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-4889 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Death Dis <i>Subsets: </i>MEDLINE
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