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CRISPR-induced RASGAP deficiencies in colorectal cancer organoids reveal that only loss of NF1 promotes resistance to EGFR inhibition.

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Title: CRISPR-induced RASGAP deficiencies in colorectal cancer organoids reveal that only loss of NF1 promotes resistance to EGFR inhibition.
Authors: Post JB; Center for Molecular Medicine, Section Molecular Cancer Research, University Medical Center Utrecht, Utrecht, The Netherlands.; Oncode Netherlands, Institute Netherlands, Office Jaarbeurs Innovation Mile, Utrecht, The Netherlands., Hami N; Center for Molecular Medicine, Section Molecular Cancer Research, University Medical Center Utrecht, Utrecht, The Netherlands.; Oncode Netherlands, Institute Netherlands, Office Jaarbeurs Innovation Mile, Utrecht, The Netherlands., Mertens AEE; Center for Molecular Medicine, Section Molecular Cancer Research, University Medical Center Utrecht, Utrecht, The Netherlands.; Oncode Netherlands, Institute Netherlands, Office Jaarbeurs Innovation Mile, Utrecht, The Netherlands., Elfrink S; Center for Molecular Medicine, Section Molecular Cancer Research, University Medical Center Utrecht, Utrecht, The Netherlands.; Oncode Netherlands, Institute Netherlands, Office Jaarbeurs Innovation Mile, Utrecht, The Netherlands., Bos JL; Center for Molecular Medicine, Section Molecular Cancer Research, University Medical Center Utrecht, Utrecht, The Netherlands.; Oncode Netherlands, Institute Netherlands, Office Jaarbeurs Innovation Mile, Utrecht, The Netherlands., Snippert HJG; Center for Molecular Medicine, Section Molecular Cancer Research, University Medical Center Utrecht, Utrecht, The Netherlands.; Oncode Netherlands, Institute Netherlands, Office Jaarbeurs Innovation Mile, Utrecht, The Netherlands.
Source: Oncotarget [Oncotarget] 2019 Feb 15; Vol. 10 (14), pp. 1440-1457. Date of Electronic Publication: 2019 Feb 15 (Print Publication: 2019).
Publication Type: Journal Article
Journal Info: Publisher: Impact Journals Country of Publication: United States NLM ID: 101532965 Publication Model: eCollection Cited Medium: Internet ISSN: 1949-2553 (Electronic) Linking ISSN: 19492553 NLM ISO Abbreviation: Oncotarget Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: CRISPR-induced RASGAP deficiencies in colorectal cancer organoids reveal that only loss of NF1 promotes resistance to EGFR inhibition.
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  Data: <searchLink fieldCode="AU" term="%22Post+JB%22">Post JB</searchLink>; Center for Molecular Medicine, Section Molecular Cancer Research, University Medical Center Utrecht, Utrecht, The Netherlands.; Oncode Netherlands, Institute Netherlands, Office Jaarbeurs Innovation Mile, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Hami+N%22">Hami N</searchLink>; Center for Molecular Medicine, Section Molecular Cancer Research, University Medical Center Utrecht, Utrecht, The Netherlands.; Oncode Netherlands, Institute Netherlands, Office Jaarbeurs Innovation Mile, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Mertens+AEE%22">Mertens AEE</searchLink>; Center for Molecular Medicine, Section Molecular Cancer Research, University Medical Center Utrecht, Utrecht, The Netherlands.; Oncode Netherlands, Institute Netherlands, Office Jaarbeurs Innovation Mile, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Elfrink+S%22">Elfrink S</searchLink>; Center for Molecular Medicine, Section Molecular Cancer Research, University Medical Center Utrecht, Utrecht, The Netherlands.; Oncode Netherlands, Institute Netherlands, Office Jaarbeurs Innovation Mile, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bos+JL%22">Bos JL</searchLink>; Center for Molecular Medicine, Section Molecular Cancer Research, University Medical Center Utrecht, Utrecht, The Netherlands.; Oncode Netherlands, Institute Netherlands, Office Jaarbeurs Innovation Mile, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Snippert+HJG%22">Snippert HJG</searchLink>; Center for Molecular Medicine, Section Molecular Cancer Research, University Medical Center Utrecht, Utrecht, The Netherlands.; Oncode Netherlands, Institute Netherlands, Office Jaarbeurs Innovation Mile, Utrecht, The Netherlands.
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  Data: <searchLink fieldCode="JN" term="%22101532965%22">Oncotarget</searchLink> [Oncotarget] 2019 Feb 15; Vol. 10 (14), pp. 1440-1457. <i>Date of Electronic Publication: </i>2019 Feb 15 (<i>Print Publication: </i>2019).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Impact+Journals%22">Impact Journals </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101532965 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1949-2553 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219492553%22">19492553 </searchLink><i>NLM ISO Abbreviation: </i>Oncotarget <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2019 Feb 15
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