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Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth.

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Title: Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth.
Authors: Thilakasiri P; Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Heidelberg, Vic., Australia., Huynh J; Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Heidelberg, Vic., Australia., Poh AR; Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Heidelberg, Vic., Australia., Tan CW; The Walter and Eliza Hall Institute, Melbourne, Vic., Australia., Nero TL; ACRF Rational Drug Discovery Centre, St Vincent's Institute, Melbourne, Vic., Australia.; Department of Biochemistry and Molecular Biology, Bio21 Institute, University of Melbourne, Melbourne, Vic., Australia., Tran K; Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Heidelberg, Vic., Australia., Parslow AC; Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Heidelberg, Vic., Australia.; Department of Molecular Imaging and Therapy, Austin Health, Melbourne, Vic., Australia., Afshar-Sterle S; Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Heidelberg, Vic., Australia., Baloyan D; Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Heidelberg, Vic., Australia., Hannan NJ; Department of Obstetrics and Gynaecology, University of Melbourne, Melbourne, Vic., Australia., Buchert M; Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Heidelberg, Vic., Australia., Scott AM; Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Heidelberg, Vic., Australia.; Department of Molecular Imaging and Therapy, Austin Health, Melbourne, Vic., Australia.; Department of Medicine, University of Melbourne, Melbourne, Vic., Australia., Griffin MD; Department of Biochemistry and Molecular Biology, Bio21 Institute, University of Melbourne, Melbourne, Vic., Australia., Hollande F; Department of Clinical Pathology, University of Melbourne Centre for Cancer Research, Victorian Comprehensive Cancer Centre, University of Melbourne, Melbourne, Vic., Australia., Parker MW; ACRF Rational Drug Discovery Centre, St Vincent's Institute, Melbourne, Vic., Australia.; Department of Biochemistry and Molecular Biology, Bio21 Institute, University of Melbourne, Melbourne, Vic., Australia., Putoczki TL; The Walter and Eliza Hall Institute, Melbourne, Vic., Australia., Ernst M; Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Heidelberg, Vic., Australia matthias.ernst@onjcri.org.au ashwini.chand@onjcri.org.au., Chand AL; Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Heidelberg, Vic., Australia matthias.ernst@onjcri.org.au ashwini.chand@onjcri.org.au.
Source: EMBO molecular medicine [EMBO Mol Med] 2019 Apr; Vol. 11 (4).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth.
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  Data: <searchLink fieldCode="AU" term="%22Thilakasiri+P%22">Thilakasiri P</searchLink>; Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Heidelberg, Vic., Australia.<br /><searchLink fieldCode="AU" term="%22Huynh+J%22">Huynh J</searchLink>; Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Heidelberg, Vic., Australia.<br /><searchLink fieldCode="AU" term="%22Poh+AR%22">Poh AR</searchLink>; Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Heidelberg, Vic., Australia.<br /><searchLink fieldCode="AU" term="%22Tan+CW%22">Tan CW</searchLink>; The Walter and Eliza Hall Institute, Melbourne, Vic., Australia.<br /><searchLink fieldCode="AU" term="%22Nero+TL%22">Nero TL</searchLink>; ACRF Rational Drug Discovery Centre, St Vincent's Institute, Melbourne, Vic., Australia.; Department of Biochemistry and Molecular Biology, Bio21 Institute, University of Melbourne, Melbourne, Vic., Australia.<br /><searchLink fieldCode="AU" term="%22Tran+K%22">Tran K</searchLink>; Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Heidelberg, Vic., Australia.<br /><searchLink fieldCode="AU" term="%22Parslow+AC%22">Parslow AC</searchLink>; Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Heidelberg, Vic., Australia.; Department of Molecular Imaging and Therapy, Austin Health, Melbourne, Vic., Australia.<br /><searchLink fieldCode="AU" term="%22Afshar-Sterle+S%22">Afshar-Sterle S</searchLink>; Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Heidelberg, Vic., Australia.<br /><searchLink fieldCode="AU" term="%22Baloyan+D%22">Baloyan D</searchLink>; Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Heidelberg, Vic., Australia.<br /><searchLink fieldCode="AU" term="%22Hannan+NJ%22">Hannan NJ</searchLink>; Department of Obstetrics and Gynaecology, University of Melbourne, Melbourne, Vic., Australia.<br /><searchLink fieldCode="AU" term="%22Buchert+M%22">Buchert M</searchLink>; Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Heidelberg, Vic., Australia.<br /><searchLink fieldCode="AU" term="%22Scott+AM%22">Scott AM</searchLink>; Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Heidelberg, Vic., Australia.; Department of Molecular Imaging and Therapy, Austin Health, Melbourne, Vic., Australia.; Department of Medicine, University of Melbourne, Melbourne, Vic., Australia.<br /><searchLink fieldCode="AU" term="%22Griffin+MD%22">Griffin MD</searchLink>; Department of Biochemistry and Molecular Biology, Bio21 Institute, University of Melbourne, Melbourne, Vic., Australia.<br /><searchLink fieldCode="AU" term="%22Hollande+F%22">Hollande F</searchLink>; Department of Clinical Pathology, University of Melbourne Centre for Cancer Research, Victorian Comprehensive Cancer Centre, University of Melbourne, Melbourne, Vic., Australia.<br /><searchLink fieldCode="AU" term="%22Parker+MW%22">Parker MW</searchLink>; ACRF Rational Drug Discovery Centre, St Vincent's Institute, Melbourne, Vic., Australia.; Department of Biochemistry and Molecular Biology, Bio21 Institute, University of Melbourne, Melbourne, Vic., Australia.<br /><searchLink fieldCode="AU" term="%22Putoczki+TL%22">Putoczki TL</searchLink>; The Walter and Eliza Hall Institute, Melbourne, Vic., Australia.<br /><searchLink fieldCode="AU" term="%22Ernst+M%22">Ernst M</searchLink>; Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Heidelberg, Vic., Australia matthias.ernst@onjcri.org.au ashwini.chand@onjcri.org.au.<br /><searchLink fieldCode="AU" term="%22Chand+AL%22">Chand AL</searchLink>; Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Heidelberg, Vic., Australia matthias.ernst@onjcri.org.au ashwini.chand@onjcri.org.au.
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