Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies. - Raman S; Beilschmidt M; To M; Lin K; Lui F; Jmeian Y; Ng M; Fernandez M; Fu Y; Mascall K; Duque A; Wang X; et al. (Proceedings of the National Academy of Sciences of the United States of America, 2019)