Allele-specific binding of RNA-binding proteins reveals functional genetic variants in the RNA.
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| Title: | Allele-specific binding of RNA-binding proteins reveals functional genetic variants in the RNA. |
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| Authors: | Yang EW; Department of Integrative Biology and Physiology, UCLA, Los Angeles, CA, 90095, USA., Bahn JH; Department of Integrative Biology and Physiology, UCLA, Los Angeles, CA, 90095, USA., Hsiao EY; Department of Integrative Biology and Physiology, UCLA, Los Angeles, CA, 90095, USA.; Department of Bioengineering, UCLA, Los Angeles, CA, 90095, USA., Tan BX; Department of Integrative Biology and Physiology, UCLA, Los Angeles, CA, 90095, USA., Sun Y; Department of Integrative Biology and Physiology, UCLA, Los Angeles, CA, 90095, USA., Fu T; Department of Integrative Biology and Physiology, UCLA, Los Angeles, CA, 90095, USA.; Molecular, Cellular and Integrative Physiology Interdepartmental Program, UCLA, Los Angeles, CA, 90095, USA., Zhou B; Department of Psychiatry and Behavioral Sciences, Department of Genetics, Stanford University School of Medicine, Palo Alto, CA, 94305, USA., Van Nostrand EL; Department of Cellular and Molecular Medicine, UCSD, La Jolla, CA, 92093, USA.; Institute for Genomic Medicine, UCSD, La Jolla, CA, 92093, USA., Pratt GA; Department of Cellular and Molecular Medicine, UCSD, La Jolla, CA, 92093, USA.; Institute for Genomic Medicine, UCSD, La Jolla, CA, 92093, USA., Freese P; Department of Biology, MIT, Cambridge, MA, 02139, USA., Wei X; Department of Genetics and Genome Sciences, Institute for Systems Genomics, UConn Health, Farmington, CT, 06030, USA., Quinones-Valdez G; Department of Bioengineering, UCLA, Los Angeles, CA, 90095, USA., Urban AE; Department of Psychiatry and Behavioral Sciences, Department of Genetics, Stanford University School of Medicine, Palo Alto, CA, 94305, USA., Graveley BR; Department of Genetics and Genome Sciences, Institute for Systems Genomics, UConn Health, Farmington, CT, 06030, USA., Burge CB; Department of Biology, MIT, Cambridge, MA, 02139, USA., Yeo GW; Department of Cellular and Molecular Medicine, UCSD, La Jolla, CA, 92093, USA.; Institute for Genomic Medicine, UCSD, La Jolla, CA, 92093, USA.; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117593, Singapore.; Molecular Engineering Laboratory, A*STAR, Singapore, 138673, Singapore., Xiao X; Department of Integrative Biology and Physiology, UCLA, Los Angeles, CA, 90095, USA. gxxiao@ucla.edu.; Department of Bioengineering, UCLA, Los Angeles, CA, 90095, USA. gxxiao@ucla.edu.; Molecular, Cellular and Integrative Physiology Interdepartmental Program, UCLA, Los Angeles, CA, 90095, USA. gxxiao@ucla.edu.; Molecular Biology Institute, UCLA, Los Angeles, CA, 90095, USA. gxxiao@ucla.edu. |
| Source: | Nature communications [Nat Commun] 2019 Mar 22; Vol. 10 (1), pp. 1338. Date of Electronic Publication: 2019 Mar 22. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-019-09292-w |
