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Cytotoxic synergy between alisertib and carboplatin versus alisertib and irinotecan are inversely dependent on MGMT levels in glioblastoma cells.

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Title: Cytotoxic synergy between alisertib and carboplatin versus alisertib and irinotecan are inversely dependent on MGMT levels in glioblastoma cells.
Authors: Sak M; Department of Pathology and Laboratory Medicine, University of Louisville, Louisville, KY, 40202, USA.; Department of Biochemistry and Molecular Genetics, University of Louisville, Louisville, KY, 40202, USA., Zumbar CT; Department of Pathology and Laboratory Medicine, University of Louisville, Louisville, KY, 40202, USA., King PD; The Department of Pathology, Ohio State University, Columbus, OH, 43212, USA., Li X; The Department of Pathology, Ohio State University, Columbus, OH, 43212, USA., Mifsud CS; The Department of Pathology, Ohio State University, Columbus, OH, 43212, USA., Usubalieva A; The Department of Pathology, Ohio State University, Columbus, OH, 43212, USA., Anderson CD; Department of Pathology and Laboratory Medicine, University of Louisville, Louisville, KY, 40202, USA., Chesnick HM; The Department of Pathology, Ohio State University, Columbus, OH, 43212, USA., McElroy JP; Department of Biomedical Informatics, Ohio State University, Columbus, OH, 43212, USA., Chakravarti A; Department of Radiation Oncology, Ohio State University, Columbus, OH, 43212, USA., Burton EC; Neuro-Oncology Branch, National Cancer Institute, Bethesda, MD, 20892, USA., Lehman NL; Department of Pathology and Laboratory Medicine, University of Louisville, Louisville, KY, 40202, USA. nllehman1@gmail.com.; Department of Biochemistry and Molecular Genetics, University of Louisville, Louisville, KY, 40202, USA. nllehman1@gmail.com.; The Brown Cancer Center, University of Louisville, Louisville, KY, 40202, USA. nllehman1@gmail.com.
Source: Journal of neuro-oncology [J Neurooncol] 2019 Jun; Vol. 143 (2), pp. 231-240. Date of Electronic Publication: 2019 Apr 22.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 8309335 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7373 (Electronic) Linking ISSN: 0167594X NLM ISO Abbreviation: J Neurooncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cytotoxic synergy between alisertib and carboplatin versus alisertib and irinotecan are inversely dependent on MGMT levels in glioblastoma cells.
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  Data: <searchLink fieldCode="AU" term="%22Sak+M%22">Sak M</searchLink>; Department of Pathology and Laboratory Medicine, University of Louisville, Louisville, KY, 40202, USA.; Department of Biochemistry and Molecular Genetics, University of Louisville, Louisville, KY, 40202, USA.<br /><searchLink fieldCode="AU" term="%22Zumbar+CT%22">Zumbar CT</searchLink>; Department of Pathology and Laboratory Medicine, University of Louisville, Louisville, KY, 40202, USA.<br /><searchLink fieldCode="AU" term="%22King+PD%22">King PD</searchLink>; The Department of Pathology, Ohio State University, Columbus, OH, 43212, USA.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; The Department of Pathology, Ohio State University, Columbus, OH, 43212, USA.<br /><searchLink fieldCode="AU" term="%22Mifsud+CS%22">Mifsud CS</searchLink>; The Department of Pathology, Ohio State University, Columbus, OH, 43212, USA.<br /><searchLink fieldCode="AU" term="%22Usubalieva+A%22">Usubalieva A</searchLink>; The Department of Pathology, Ohio State University, Columbus, OH, 43212, USA.<br /><searchLink fieldCode="AU" term="%22Anderson+CD%22">Anderson CD</searchLink>; Department of Pathology and Laboratory Medicine, University of Louisville, Louisville, KY, 40202, USA.<br /><searchLink fieldCode="AU" term="%22Chesnick+HM%22">Chesnick HM</searchLink>; The Department of Pathology, Ohio State University, Columbus, OH, 43212, USA.<br /><searchLink fieldCode="AU" term="%22McElroy+JP%22">McElroy JP</searchLink>; Department of Biomedical Informatics, Ohio State University, Columbus, OH, 43212, USA.<br /><searchLink fieldCode="AU" term="%22Chakravarti+A%22">Chakravarti A</searchLink>; Department of Radiation Oncology, Ohio State University, Columbus, OH, 43212, USA.<br /><searchLink fieldCode="AU" term="%22Burton+EC%22">Burton EC</searchLink>; Neuro-Oncology Branch, National Cancer Institute, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Lehman+NL%22">Lehman NL</searchLink>; Department of Pathology and Laboratory Medicine, University of Louisville, Louisville, KY, 40202, USA. nllehman1@gmail.com.; Department of Biochemistry and Molecular Genetics, University of Louisville, Louisville, KY, 40202, USA. nllehman1@gmail.com.; The Brown Cancer Center, University of Louisville, Louisville, KY, 40202, USA. nllehman1@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%228309335%22">Journal of neuro-oncology</searchLink> [J Neurooncol] 2019 Jun; Vol. 143 (2), pp. 231-240. <i>Date of Electronic Publication: </i>2019 Apr 22.
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