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Perioperative systemic therapy and cytoreductive surgery with HIPEC versus upfront cytoreductive surgery with HIPEC alone for isolated resectable colorectal peritoneal metastases: protocol of a multicentre, open-label, parallel-group, phase II-III, randomised, superiority study (CAIRO6)

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Title: Perioperative systemic therapy and cytoreductive surgery with HIPEC versus upfront cytoreductive surgery with HIPEC alone for isolated resectable colorectal peritoneal metastases: protocol of a multicentre, open-label, parallel-group, phase II-III, randomised, superiority study (CAIRO6)
Authors: Rovers KP; Department of Surgery, Catharina Hospital, PO Box 1350, 5602 ZA, Eindhoven, Netherlands., Bakkers C; Department of Surgery, Catharina Hospital, PO Box 1350, 5602 ZA, Eindhoven, Netherlands., Simkens GAAM; Department of Surgery, Catharina Hospital, PO Box 1350, 5602 ZA, Eindhoven, Netherlands., Burger JWA; Department of Surgery, Catharina Hospital, PO Box 1350, 5602 ZA, Eindhoven, Netherlands., Nienhuijs SW; Department of Surgery, Catharina Hospital, PO Box 1350, 5602 ZA, Eindhoven, Netherlands., Creemers GM; Department of Medical Oncology, Catharina Hospital, PO Box 1350, 5602, Eindhoven, ZA, Netherlands., Thijs AMJ; Department of Medical Oncology, Catharina Hospital, PO Box 1350, 5602, Eindhoven, ZA, Netherlands., Brandt-Kerkhof ARM; Department of Surgical Oncology, Erasmus Medical Centre, PO Box 2040, 3000, Rotterdam, CA, Netherlands., Madsen EVE; Department of Surgical Oncology, Erasmus Medical Centre, PO Box 2040, 3000, Rotterdam, CA, Netherlands., Ayez N; Department of Surgical Oncology, Erasmus Medical Centre, PO Box 2040, 3000, Rotterdam, CA, Netherlands., de Boer NL; Department of Surgical Oncology, Erasmus Medical Centre, PO Box 2040, 3000, Rotterdam, CA, Netherlands., van Meerten E; Department of Medical Oncology, Erasmus MC Cancer Institute, PO Box 2040, 3000, Rotterdam, CA, Netherlands., Tuynman JB; Department of Surgery, Amsterdam University Medical Centres, Location VUMC, PO Box 7057, 1007, Amsterdam, MB, Netherlands., Kusters M; Department of Surgery, Amsterdam University Medical Centres, Location VUMC, PO Box 7057, 1007, Amsterdam, MB, Netherlands., Sluiter NR; Department of Surgery, Amsterdam University Medical Centres, Location VUMC, PO Box 7057, 1007, Amsterdam, MB, Netherlands., Verheul HMW; Department of Medical Oncology, Amsterdam University Medical Centres, Location VUMC, PO Box 7057, 1007, Amsterdam, MB, Netherlands., van der Vliet HJ; Department of Medical Oncology, Amsterdam University Medical Centres, Location VUMC, PO Box 7057, 1007, Amsterdam, MB, Netherlands., Wiezer MJ; Department of Surgery, St. Antonius Hospital, PO Box 2500, 3430, Nieuwegein, EM, Netherlands., Boerma D; Department of Surgery, St. Antonius Hospital, PO Box 2500, 3430, Nieuwegein, EM, Netherlands., Wassenaar ECE; Department of Surgery, St. Antonius Hospital, PO Box 2500, 3430, Nieuwegein, EM, Netherlands., Los M; Department of Medical Oncology, St. Antonius Hospital, PO Box 2500, 3430, Nieuwegein, EM, Netherlands., Hunting CB; Department of Medical Oncology, St. Antonius Hospital, PO Box 2500, 3430, Nieuwegein, EM, Netherlands., Aalbers AGJ; Department of Surgical Oncology, Netherlands Cancer Institute, PO Box 90203, 1006, Amsterdam, BE, Netherlands., Kok NFM; Department of Surgical Oncology, Netherlands Cancer Institute, PO Box 90203, 1006, Amsterdam, BE, Netherlands., Kuhlmann KFD; Department of Surgical Oncology, Netherlands Cancer Institute, PO Box 90203, 1006, Amsterdam, BE, Netherlands., Boot H; Department of Gastrointestinal Oncology, Netherlands Cancer Institute, PO Box 90203, 1006, Amsterdam, BE, Netherlands., Chalabi M; Department of Gastrointestinal Oncology, Netherlands Cancer Institute, PO Box 90203, 1006, Amsterdam, BE, Netherlands., Kruijff S; Department of Surgery, University Medical Centre Groningen, PO Box 30001, 9700 RB, Groningen, RB, Netherlands., Been LB; Department of Surgery, University Medical Centre Groningen, PO Box 30001, 9700 RB, Groningen, RB, Netherlands., van Ginkel RJ; Department of Surgery, University Medical Centre Groningen, PO Box 30001, 9700 RB, Groningen, RB, Netherlands., de Groot DJA; Department of Medical Oncology, University Medical Centre Groningen, PO Box 30001, 9700, Groningen, RB, Netherlands., Fehrmann RSN; Department of Medical Oncology, University Medical Centre Groningen, PO Box 30001, 9700, Groningen, RB, Netherlands., de Wilt JHW; Department of Surgery, Radboud University Medical Centre, PO Box 9101, 6500, Nijmegen, HB, Netherlands., Bremers AJA; Department of Surgery, Radboud University Medical Centre, PO Box 9101, 6500, Nijmegen, HB, Netherlands., de Reuver PR; Department of Surgery, Radboud University Medical Centre, PO Box 9101, 6500, Nijmegen, HB, Netherlands., Radema SA; Department of Medical Oncology, Radboud University Medical Centre, PO Box 9101, 6500, Nijmegen, HB, Netherlands., Herbschleb KH; Department of Medical Oncology, Radboud University Medical Centre, PO Box 9101, 6500, Nijmegen, HB, Netherlands., van Grevenstein WMU; Department of Surgery, University Medical Centre Utrecht, PO Box 85500, 3508, Utrecht, GA, Netherlands., Witkamp AJ; Department of Surgery, University Medical Centre Utrecht, PO Box 85500, 3508, Utrecht, GA, Netherlands., Koopman M; Department of Medical Oncology, University Medical Centre Utrecht, PO Box 85500, 3508, Utrecht, GA, Netherlands., Haj Mohammad N; Department of Medical Oncology, University Medical Centre Utrecht, PO Box 85500, 3508, Utrecht, GA, Netherlands., van Duyn EB; Department of Surgery, Medisch Spectrum Twente, PO Box 50000, 7500, Enschede, KA, Netherlands., Mastboom WJB; Department of Surgery, Medisch Spectrum Twente, PO Box 50000, 7500, Enschede, KA, Netherlands., Mekenkamp LJM; Department of Medical Oncology, Medisch Spectrum Twente, PO Box 50000, 7500, Enschede, KA, Netherlands., Nederend J; Department of Radiology, Catharina Hospital, PO Box 1350, 5602, Eindhoven, ZA, Netherlands., Lahaye MJ; Department of Radiology, Netherlands Cancer Institute, PO Box 90203, 1006, Amsterdam, BE, Netherlands., Snaebjornsson P; Department of Pathology, Netherlands Cancer Institute, PO Box 90203, 1006, Amsterdam, BE, Netherlands., Verhoef C; Department of Surgical Oncology, Erasmus Medical Centre, PO Box 2040, 3000, Rotterdam, CA, Netherlands., van Laarhoven HWM; Department of Medical Oncology, Amsterdam University Medical Centres, Location AMC, PO Box 22660, 1100, Amsterdam, DD, Netherlands., Zwinderman AH; Department of Clinical Epidemiology, Biostatistics & Bioinformatics, Amsterdam University Medical Centres, Location AMC, PO Box 22660, 1100, Amsterdam, DD, Netherlands., Bouma JM; Clinical Trial Department, Netherlands Comprehensive Cancer Organisation (IKNL), PO Box 19079, 3501, Utrecht, DB, Netherlands., Kranenburg O; UMC Utrecht Cancer Centre, University Medical Centre Utrecht, PO Box 85500, 3508, Utrecht, GA, Netherlands., van 't Erve I; Department of Pathology, Netherlands Cancer Institute, PO Box 90203, 1006, Amsterdam, BE, Netherlands., Fijneman RJA; Department of Pathology, Netherlands Cancer Institute, PO Box 90203, 1006, Amsterdam, BE, Netherlands., Dijkgraaf MGW; Department of Clinical Epidemiology, Biostatistics & Bioinformatics, Amsterdam University Medical Centres, Location AMC, PO Box 22660, 1100, Amsterdam, DD, Netherlands., Hemmer PHJ; Department of Surgery, University Medical Centre Groningen, PO Box 30001, 9700 RB, Groningen, RB, Netherlands., Punt CJA; Department of Medical Oncology, Amsterdam University Medical Centres, Location AMC, PO Box 22660, 1100, Amsterdam, DD, Netherlands., Tanis PJ; Department of Surgery, Amsterdam University Medical Centres, Location AMC, PO Box 22660, 1100, Amsterdam, DD, Netherlands., de Hingh IHJT; Department of Surgery, Catharina Hospital, PO Box 1350, 5602 ZA, Eindhoven, Netherlands. ignace.d.hingh@catharinaziekenhuis.nl.
Corporate Authors: Dutch Peritoneal Oncology Group (DPOG), Dutch Colorectal Cancer Group (DCCG)
Source: BMC cancer [BMC Cancer] 2019 Apr 25; Vol. 19 (1), pp. 390. Date of Electronic Publication: 2019 Apr 25.
Publication Type: Clinical Trial Protocol; Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer
Database: MEDLINE Ultimate
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Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 31023318
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  Data: Perioperative systemic therapy and cytoreductive surgery with HIPEC versus upfront cytoreductive surgery with HIPEC alone for isolated resectable colorectal peritoneal metastases: protocol of a multicentre, open-label, parallel-group, phase II-III, randomised, superiority study (CAIRO6)
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  Label: Authors
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  Data: <searchLink fieldCode="AU" term="%22Rovers+KP%22">Rovers KP</searchLink>; Department of Surgery, Catharina Hospital, PO Box 1350, 5602 ZA, Eindhoven, Netherlands.<br /><searchLink fieldCode="AU" term="%22Bakkers+C%22">Bakkers C</searchLink>; Department of Surgery, Catharina Hospital, PO Box 1350, 5602 ZA, Eindhoven, Netherlands.<br /><searchLink fieldCode="AU" term="%22Simkens+GAAM%22">Simkens GAAM</searchLink>; Department of Surgery, Catharina Hospital, PO Box 1350, 5602 ZA, Eindhoven, Netherlands.<br /><searchLink fieldCode="AU" term="%22Burger+JWA%22">Burger JWA</searchLink>; Department of Surgery, Catharina Hospital, PO Box 1350, 5602 ZA, Eindhoven, Netherlands.<br /><searchLink fieldCode="AU" term="%22Nienhuijs+SW%22">Nienhuijs SW</searchLink>; Department of Surgery, Catharina Hospital, PO Box 1350, 5602 ZA, Eindhoven, Netherlands.<br /><searchLink fieldCode="AU" term="%22Creemers+GM%22">Creemers GM</searchLink>; Department of Medical Oncology, Catharina Hospital, PO Box 1350, 5602, Eindhoven, ZA, Netherlands.<br /><searchLink fieldCode="AU" term="%22Thijs+AMJ%22">Thijs AMJ</searchLink>; Department of Medical Oncology, Catharina Hospital, PO Box 1350, 5602, Eindhoven, ZA, Netherlands.<br /><searchLink fieldCode="AU" term="%22Brandt-Kerkhof+ARM%22">Brandt-Kerkhof ARM</searchLink>; Department of Surgical Oncology, Erasmus Medical Centre, PO Box 2040, 3000, Rotterdam, CA, Netherlands.<br /><searchLink fieldCode="AU" term="%22Madsen+EVE%22">Madsen EVE</searchLink>; Department of Surgical Oncology, Erasmus Medical Centre, PO Box 2040, 3000, Rotterdam, CA, Netherlands.<br /><searchLink fieldCode="AU" term="%22Ayez+N%22">Ayez N</searchLink>; Department of Surgical Oncology, Erasmus Medical Centre, PO Box 2040, 3000, Rotterdam, CA, Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Boer+NL%22">de Boer NL</searchLink>; Department of Surgical Oncology, Erasmus Medical Centre, PO Box 2040, 3000, Rotterdam, CA, Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Meerten+E%22">van Meerten E</searchLink>; Department of Medical Oncology, Erasmus MC Cancer Institute, PO Box 2040, 3000, Rotterdam, CA, Netherlands.<br /><searchLink fieldCode="AU" term="%22Tuynman+JB%22">Tuynman JB</searchLink>; Department of Surgery, Amsterdam University Medical Centres, Location VUMC, PO Box 7057, 1007, Amsterdam, MB, Netherlands.<br /><searchLink fieldCode="AU" term="%22Kusters+M%22">Kusters M</searchLink>; Department of Surgery, Amsterdam University Medical Centres, Location VUMC, PO Box 7057, 1007, Amsterdam, MB, Netherlands.<br /><searchLink fieldCode="AU" term="%22Sluiter+NR%22">Sluiter NR</searchLink>; Department of Surgery, Amsterdam University Medical Centres, Location VUMC, PO Box 7057, 1007, Amsterdam, MB, Netherlands.<br /><searchLink fieldCode="AU" term="%22Verheul+HMW%22">Verheul HMW</searchLink>; Department of Medical Oncology, Amsterdam University Medical Centres, Location VUMC, PO Box 7057, 1007, Amsterdam, MB, Netherlands.<br /><searchLink fieldCode="AU" term="%22van+der+Vliet+HJ%22">van der Vliet HJ</searchLink>; Department of Medical Oncology, Amsterdam University Medical Centres, Location VUMC, PO Box 7057, 1007, Amsterdam, MB, Netherlands.<br /><searchLink fieldCode="AU" term="%22Wiezer+MJ%22">Wiezer MJ</searchLink>; Department of Surgery, St. Antonius Hospital, PO Box 2500, 3430, Nieuwegein, EM, Netherlands.<br /><searchLink fieldCode="AU" term="%22Boerma+D%22">Boerma D</searchLink>; Department of Surgery, St. Antonius Hospital, PO Box 2500, 3430, Nieuwegein, EM, Netherlands.<br /><searchLink fieldCode="AU" term="%22Wassenaar+ECE%22">Wassenaar ECE</searchLink>; Department of Surgery, St. Antonius Hospital, PO Box 2500, 3430, Nieuwegein, EM, Netherlands.<br /><searchLink fieldCode="AU" term="%22Los+M%22">Los M</searchLink>; Department of Medical Oncology, St. Antonius Hospital, PO Box 2500, 3430, Nieuwegein, EM, Netherlands.<br /><searchLink fieldCode="AU" term="%22Hunting+CB%22">Hunting CB</searchLink>; Department of Medical Oncology, St. Antonius Hospital, PO Box 2500, 3430, Nieuwegein, EM, Netherlands.<br /><searchLink fieldCode="AU" term="%22Aalbers+AGJ%22">Aalbers AGJ</searchLink>; Department of Surgical Oncology, Netherlands Cancer Institute, PO Box 90203, 1006, Amsterdam, BE, Netherlands.<br /><searchLink fieldCode="AU" term="%22Kok+NFM%22">Kok NFM</searchLink>; Department of Surgical Oncology, Netherlands Cancer Institute, PO Box 90203, 1006, Amsterdam, BE, Netherlands.<br /><searchLink fieldCode="AU" term="%22Kuhlmann+KFD%22">Kuhlmann KFD</searchLink>; Department of Surgical Oncology, Netherlands Cancer Institute, PO Box 90203, 1006, Amsterdam, BE, Netherlands.<br /><searchLink fieldCode="AU" term="%22Boot+H%22">Boot H</searchLink>; Department of Gastrointestinal Oncology, Netherlands Cancer Institute, PO Box 90203, 1006, Amsterdam, BE, Netherlands.<br /><searchLink fieldCode="AU" term="%22Chalabi+M%22">Chalabi M</searchLink>; Department of Gastrointestinal Oncology, Netherlands Cancer Institute, PO Box 90203, 1006, Amsterdam, BE, Netherlands.<br /><searchLink fieldCode="AU" term="%22Kruijff+S%22">Kruijff S</searchLink>; Department of Surgery, University Medical Centre Groningen, PO Box 30001, 9700 RB, Groningen, RB, Netherlands.<br /><searchLink fieldCode="AU" term="%22Been+LB%22">Been LB</searchLink>; Department of Surgery, University Medical Centre Groningen, PO Box 30001, 9700 RB, Groningen, RB, Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Ginkel+RJ%22">van Ginkel RJ</searchLink>; Department of Surgery, University Medical Centre Groningen, PO Box 30001, 9700 RB, Groningen, RB, Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Groot+DJA%22">de Groot DJA</searchLink>; Department of Medical Oncology, University Medical Centre Groningen, PO Box 30001, 9700, Groningen, RB, Netherlands.<br /><searchLink fieldCode="AU" term="%22Fehrmann+RSN%22">Fehrmann RSN</searchLink>; Department of Medical Oncology, University Medical Centre Groningen, PO Box 30001, 9700, Groningen, RB, Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Wilt+JHW%22">de Wilt JHW</searchLink>; Department of Surgery, Radboud University Medical Centre, PO Box 9101, 6500, Nijmegen, HB, Netherlands.<br /><searchLink fieldCode="AU" term="%22Bremers+AJA%22">Bremers AJA</searchLink>; Department of Surgery, Radboud University Medical Centre, PO Box 9101, 6500, Nijmegen, HB, Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Reuver+PR%22">de Reuver PR</searchLink>; Department of Surgery, Radboud University Medical Centre, PO Box 9101, 6500, Nijmegen, HB, Netherlands.<br /><searchLink fieldCode="AU" term="%22Radema+SA%22">Radema SA</searchLink>; Department of Medical Oncology, Radboud University Medical Centre, PO Box 9101, 6500, Nijmegen, HB, Netherlands.<br /><searchLink fieldCode="AU" term="%22Herbschleb+KH%22">Herbschleb KH</searchLink>; Department of Medical Oncology, Radboud University Medical Centre, PO Box 9101, 6500, Nijmegen, HB, Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Grevenstein+WMU%22">van Grevenstein WMU</searchLink>; Department of Surgery, University Medical Centre Utrecht, PO Box 85500, 3508, Utrecht, GA, Netherlands.<br /><searchLink fieldCode="AU" term="%22Witkamp+AJ%22">Witkamp AJ</searchLink>; Department of Surgery, University Medical Centre Utrecht, PO Box 85500, 3508, Utrecht, GA, Netherlands.<br /><searchLink fieldCode="AU" term="%22Koopman+M%22">Koopman M</searchLink>; Department of Medical Oncology, University Medical Centre Utrecht, PO Box 85500, 3508, Utrecht, GA, Netherlands.<br /><searchLink fieldCode="AU" term="%22Haj+Mohammad+N%22">Haj Mohammad N</searchLink>; Department of Medical Oncology, University Medical Centre Utrecht, PO Box 85500, 3508, Utrecht, GA, Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Duyn+EB%22">van Duyn EB</searchLink>; Department of Surgery, Medisch Spectrum Twente, PO Box 50000, 7500, Enschede, KA, Netherlands.<br /><searchLink fieldCode="AU" term="%22Mastboom+WJB%22">Mastboom WJB</searchLink>; Department of Surgery, Medisch Spectrum Twente, PO Box 50000, 7500, Enschede, KA, Netherlands.<br /><searchLink fieldCode="AU" term="%22Mekenkamp+LJM%22">Mekenkamp LJM</searchLink>; Department of Medical Oncology, Medisch Spectrum Twente, PO Box 50000, 7500, Enschede, KA, Netherlands.<br /><searchLink fieldCode="AU" term="%22Nederend+J%22">Nederend J</searchLink>; Department of Radiology, Catharina Hospital, PO Box 1350, 5602, Eindhoven, ZA, Netherlands.<br /><searchLink fieldCode="AU" term="%22Lahaye+MJ%22">Lahaye MJ</searchLink>; Department of Radiology, Netherlands Cancer Institute, PO Box 90203, 1006, Amsterdam, BE, Netherlands.<br /><searchLink fieldCode="AU" term="%22Snaebjornsson+P%22">Snaebjornsson P</searchLink>; Department of Pathology, Netherlands Cancer Institute, PO Box 90203, 1006, Amsterdam, BE, Netherlands.<br /><searchLink fieldCode="AU" term="%22Verhoef+C%22">Verhoef C</searchLink>; Department of Surgical Oncology, Erasmus Medical Centre, PO Box 2040, 3000, Rotterdam, CA, Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Laarhoven+HWM%22">van Laarhoven HWM</searchLink>; Department of Medical Oncology, Amsterdam University Medical Centres, Location AMC, PO Box 22660, 1100, Amsterdam, DD, Netherlands.<br /><searchLink fieldCode="AU" term="%22Zwinderman+AH%22">Zwinderman AH</searchLink>; Department of Clinical Epidemiology, Biostatistics & Bioinformatics, Amsterdam University Medical Centres, Location AMC, PO Box 22660, 1100, Amsterdam, DD, Netherlands.<br /><searchLink fieldCode="AU" term="%22Bouma+JM%22">Bouma JM</searchLink>; Clinical Trial Department, Netherlands Comprehensive Cancer Organisation (IKNL), PO Box 19079, 3501, Utrecht, DB, Netherlands.<br /><searchLink fieldCode="AU" term="%22Kranenburg+O%22">Kranenburg O</searchLink>; UMC Utrecht Cancer Centre, University Medical Centre Utrecht, PO Box 85500, 3508, Utrecht, GA, Netherlands.<br /><searchLink fieldCode="AU" term="%22van+'t+Erve+I%22">van 't Erve I</searchLink>; Department of Pathology, Netherlands Cancer Institute, PO Box 90203, 1006, Amsterdam, BE, Netherlands.<br /><searchLink fieldCode="AU" term="%22Fijneman+RJA%22">Fijneman RJA</searchLink>; Department of Pathology, Netherlands Cancer Institute, PO Box 90203, 1006, Amsterdam, BE, Netherlands.<br /><searchLink fieldCode="AU" term="%22Dijkgraaf+MGW%22">Dijkgraaf MGW</searchLink>; Department of Clinical Epidemiology, Biostatistics & Bioinformatics, Amsterdam University Medical Centres, Location AMC, PO Box 22660, 1100, Amsterdam, DD, Netherlands.<br /><searchLink fieldCode="AU" term="%22Hemmer+PHJ%22">Hemmer PHJ</searchLink>; Department of Surgery, University Medical Centre Groningen, PO Box 30001, 9700 RB, Groningen, RB, Netherlands.<br /><searchLink fieldCode="AU" term="%22Punt+CJA%22">Punt CJA</searchLink>; Department of Medical Oncology, Amsterdam University Medical Centres, Location AMC, PO Box 22660, 1100, Amsterdam, DD, Netherlands.<br /><searchLink fieldCode="AU" term="%22Tanis+PJ%22">Tanis PJ</searchLink>; Department of Surgery, Amsterdam University Medical Centres, Location AMC, PO Box 22660, 1100, Amsterdam, DD, Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Hingh+IHJT%22">de Hingh IHJT</searchLink>; Department of Surgery, Catharina Hospital, PO Box 1350, 5602 ZA, Eindhoven, Netherlands. ignace.d.hingh@catharinaziekenhuis.nl.
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  Data: <searchLink fieldCode="CA" term="%22Dutch+Peritoneal+Oncology+Group+%28DPOG%29%22">Dutch Peritoneal Oncology Group (DPOG)</searchLink><br /><searchLink fieldCode="CA" term="%22Dutch+Colorectal+Cancer+Group+%28DCCG%29%22">Dutch Colorectal Cancer Group (DCCG)</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22100967800%22">BMC cancer</searchLink> [BMC Cancer] 2019 Apr 25; Vol. 19 (1), pp. 390. <i>Date of Electronic Publication: </i>2019 Apr 25.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100967800 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1471-2407 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214712407%22">14712407 </searchLink><i>NLM ISO Abbreviation: </i>BMC Cancer
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      – TitleFull: Perioperative systemic therapy and cytoreductive surgery with HIPEC versus upfront cytoreductive surgery with HIPEC alone for isolated resectable colorectal peritoneal metastases: protocol of a multicentre, open-label, parallel-group, phase II-III, randomised, superiority study (CAIRO6)
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            NameFull: de Groot DJA
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          Name:
            NameFull: Fehrmann RSN
      – PersonEntity:
          Name:
            NameFull: de Wilt JHW
      – PersonEntity:
          Name:
            NameFull: Bremers AJA
      – PersonEntity:
          Name:
            NameFull: de Reuver PR
      – PersonEntity:
          Name:
            NameFull: Radema SA
      – PersonEntity:
          Name:
            NameFull: Herbschleb KH
      – PersonEntity:
          Name:
            NameFull: van Grevenstein WMU
      – PersonEntity:
          Name:
            NameFull: Witkamp AJ
      – PersonEntity:
          Name:
            NameFull: Koopman M
      – PersonEntity:
          Name:
            NameFull: Haj Mohammad N
      – PersonEntity:
          Name:
            NameFull: van Duyn EB
      – PersonEntity:
          Name:
            NameFull: Mastboom WJB
      – PersonEntity:
          Name:
            NameFull: Mekenkamp LJM
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            NameFull: Snaebjornsson P
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          Name:
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          Name:
            NameFull: Fijneman RJA
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          Name:
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            NameFull: Hemmer PHJ
      – PersonEntity:
          Name:
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      – PersonEntity:
          Name:
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          Name:
            NameFull: de Hingh IHJT
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 25
              M: 04
              Text: 2019 Apr 25
              Type: published
              Y: 2019
          Identifiers:
            – Type: issn-electronic
              Value: 1471-2407
          Numbering:
            – Type: volume
              Value: 19
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: BMC cancer
              Type: main
ResultId 1