Proteolysis targeting chimeras (PROTACs) in 'beyond rule-of-five' chemical space: Recent progress and future challenges.

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Title: Proteolysis targeting chimeras (PROTACs) in 'beyond rule-of-five' chemical space: Recent progress and future challenges.
Authors: Edmondson SD; Medicinal Chemistry, Oncology, IMED Biotech Unit, AstraZeneca, Boston, MA, USA. Electronic address: scott.edmondson@astrazeneca.com., Yang B; Medicinal Chemistry, Oncology, IMED Biotech Unit, AstraZeneca, Boston, MA, USA., Fallan C; Medicinal Chemistry, Oncology, IMED Biotech Unit, AstraZeneca, Cambridge, UK.
Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2019 Jul 01; Vol. 29 (13), pp. 1555-1564. Date of Electronic Publication: 2019 Apr 20.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Proteolysis targeting chimeras (PROTACs) in 'beyond rule-of-five' chemical space: Recent progress and future challenges.
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  Data: <searchLink fieldCode="AU" term="%22Edmondson+SD%22">Edmondson SD</searchLink>; Medicinal Chemistry, Oncology, IMED Biotech Unit, AstraZeneca, Boston, MA, USA. Electronic address: scott.edmondson@astrazeneca.com.<br /><searchLink fieldCode="AU" term="%22Yang+B%22">Yang B</searchLink>; Medicinal Chemistry, Oncology, IMED Biotech Unit, AstraZeneca, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Fallan+C%22">Fallan C</searchLink>; Medicinal Chemistry, Oncology, IMED Biotech Unit, AstraZeneca, Cambridge, UK.
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  Data: <searchLink fieldCode="JN" term="%229107377%22">Bioorganic & medicinal chemistry letters</searchLink> [Bioorg Med Chem Lett] 2019 Jul 01; Vol. 29 (13), pp. 1555-1564. <i>Date of Electronic Publication: </i>2019 Apr 20.
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        Value: 10.1016/j.bmcl.2019.04.030
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        Text: English
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        StartPage: 1555
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      – TitleFull: Proteolysis targeting chimeras (PROTACs) in 'beyond rule-of-five' chemical space: Recent progress and future challenges.
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              Text: 2019 Jul 01
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