Proteolysis targeting chimeras (PROTACs) in 'beyond rule-of-five' chemical space: Recent progress and future challenges.
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| Title: | Proteolysis targeting chimeras (PROTACs) in 'beyond rule-of-five' chemical space: Recent progress and future challenges. |
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| Authors: | Edmondson SD; Medicinal Chemistry, Oncology, IMED Biotech Unit, AstraZeneca, Boston, MA, USA. Electronic address: scott.edmondson@astrazeneca.com., Yang B; Medicinal Chemistry, Oncology, IMED Biotech Unit, AstraZeneca, Boston, MA, USA., Fallan C; Medicinal Chemistry, Oncology, IMED Biotech Unit, AstraZeneca, Cambridge, UK. |
| Source: | Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2019 Jul 01; Vol. 29 (13), pp. 1555-1564. Date of Electronic Publication: 2019 Apr 20. |
| Publication Type: | Journal Article; Review |
| Journal Info: | Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1464-3405 |
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| DOI: | 10.1016/j.bmcl.2019.04.030 |
