Functional characterization of 27 CYP3A4 protein variants to metabolize regorafenib in vitro.
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| Title: | Functional characterization of 27 CYP3A4 protein variants to metabolize regorafenib in vitro. |
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| Authors: | Li YH; Department of Pharmacology, School of Pharmacy, Wenzhou Medical University, Wenzhou, China., Lin QM; Department of Pharmacology, School of Pharmacy, Wenzhou Medical University, Wenzhou, China., Pang NH; Department of Pharmacology, School of Pharmacy, Wenzhou Medical University, Wenzhou, China., Zhang XD; Department of Pharmacology, School of Pharmacy, Wenzhou Medical University, Wenzhou, China., Huang HL; Department of Pharmacology, School of Pharmacy, Wenzhou Medical University, Wenzhou, China., Cai JP; The Key Laboratory of Geriatrics, Beijing Hospital and Beijing Institute of Geriatrics, Ministry of Health, Beijing, China., Hu GX; Department of Pharmacology, School of Pharmacy, Wenzhou Medical University, Wenzhou, China. |
| Source: | Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2019 Oct; Vol. 125 (4), pp. 337-344. Date of Electronic Publication: 2019 Jun 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Blackwell Country of Publication: England NLM ID: 101208422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-7843 (Electronic) Linking ISSN: 17427835 NLM ISO Abbreviation: Basic Clin Pharmacol Toxicol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1742-7843 |
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| DOI: | 10.1111/bcpt.13246 |