A Novel Class of Common Docking Domain Inhibitors That Prevent ERK2 Activation and Substrate Phosphorylation.

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Title: A Novel Class of Common Docking Domain Inhibitors That Prevent ERK2 Activation and Substrate Phosphorylation.
Authors: Sammons RM, Perry NA, Li Y; Torrey Pines Institute for Molecular Studies , Port St. Lucie , Florida 34987 , United States.; Department of Drug Discovery & Biomedical Sciences , University of South Carolina , Columbia , South Carolina 29208 , United States., Cho EJ, Piserchio A; Department of Chemistry and Biochemistry , The City College of New York , New York , New York 10031 , United States., Zamora-Olivares DP, Ghose R; Department of Chemistry and Biochemistry , The City College of New York , New York , New York 10031 , United States., Kaoud TS; Department of Medicinal Chemistry, Faculty of Pharmacy , Minia University , 61519 Minia , Egypt., Debevec G; Torrey Pines Institute for Molecular Studies , Port St. Lucie , Florida 34987 , United States., Bartholomeusz C, Gurevich VV, Iverson TM, Giulianotti M; Torrey Pines Institute for Molecular Studies , Port St. Lucie , Florida 34987 , United States., Houghten RA; Torrey Pines Institute for Molecular Studies , Port St. Lucie , Florida 34987 , United States., Dalby KN
Source: ACS chemical biology [ACS Chem Biol] 2019 Jun 21; Vol. 14 (6), pp. 1183-1194. Date of Electronic Publication: 2019 May 13.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1554-8937
DOI:10.1021/acschembio.9b00093