HNF4α pathway mapping identifies wild-type IDH1 as a targetable metabolic node in gastric cancer.
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| Title: | HNF4α pathway mapping identifies wild-type IDH1 as a targetable metabolic node in gastric cancer. |
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| Authors: | Xu C; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore., Ooi WF; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore, Singapore., Qamra A; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore, Singapore.; NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore, Singapore., Tan J; Laboratory of Cancer Epigenome, Department of Medical Sciences, National Cancer Centre, Singapore, Singapore.; State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, China., Chua BY; Agency for Science Technology and Research, Genome Institute of Singapore, Singapore, Singapore., Ho SWT; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore., Das K; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore., Adam Isa ZF; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore., Li Z; Laboratory of Cancer Epigenome, Department of Medical Sciences, National Cancer Centre, Singapore, Singapore., Yao X; Institute of Molecular and Cell Biology, Singapore, Singapore., Yan T; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore., Xing M; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore.; NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore, Singapore., Huang KK; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore., Lin JS; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore, Singapore., Nandi T; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore, Singapore., Tay ST; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore., Lee MH; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore., Tan ALK; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore., Ong X; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore., Ashktorab H; Department of Medicine, Howard University, Washington, DC, USA., Smoot D; Department of Internal Medicine, Meharry Medical College, Nashville, Tennessee, USA., Li S; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore.; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Ng SC; Agency for Science Technology and Research, Genome Institute of Singapore, Singapore, Singapore., Teh BT; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore.; Laboratory of Cancer Epigenome, Department of Medical Sciences, National Cancer Centre, Singapore, Singapore.; Institute of Molecular and Cell Biology, Singapore, Singapore.; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Tan P; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore.; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore, Singapore.; SingHealth/Duke-NUS Institute of Precision Medicine, National Heart Centre Singapore, Singapore, Singapore.; Cellular and Molecular Research, National Cancer Centre, Singapore, Singapore.; Singapore Gastric Cancer Consortium, Singapore, Singapore. |
| Source: | Gut [Gut] 2020 Feb; Vol. 69 (2), pp. 231-242. Date of Electronic Publication: 2019 May 08. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: British Medical Assn Country of Publication: England NLM ID: 2985108R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-3288 (Electronic) Linking ISSN: 00175749 NLM ISO Abbreviation: Gut Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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