Genetic knockout of myosin light chain kinase (MLCK210) prevents cerebral microhemorrhages and attenuates neuroinflammation in a mouse model of vascular cognitive impairment and dementia.

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Title: Genetic knockout of myosin light chain kinase (MLCK210) prevents cerebral microhemorrhages and attenuates neuroinflammation in a mouse model of vascular cognitive impairment and dementia.
Authors: Braun DJ; Sanders-Brown Center on Aging, University of Kentucky, 101 Sanders-Brown Bldg., 800 S. Limestone Street, Lexington, KY, 40536, USA., Bachstetter AD; Sanders-Brown Center on Aging, University of Kentucky, 101 Sanders-Brown Bldg., 800 S. Limestone Street, Lexington, KY, 40536, USA.; Department of Neuroscience, University of Kentucky, Lexington, KY, 40536, USA.; Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, KY, 40536, USA., Sudduth TL; Sanders-Brown Center on Aging, University of Kentucky, 101 Sanders-Brown Bldg., 800 S. Limestone Street, Lexington, KY, 40536, USA.; Department of Physiology, University of Kentucky, Lexington, KY, 40536, USA., Wilcock DM; Sanders-Brown Center on Aging, University of Kentucky, 101 Sanders-Brown Bldg., 800 S. Limestone Street, Lexington, KY, 40536, USA.; Department of Physiology, University of Kentucky, Lexington, KY, 40536, USA., Watterson DM; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA., Van Eldik LJ; Sanders-Brown Center on Aging, University of Kentucky, 101 Sanders-Brown Bldg., 800 S. Limestone Street, Lexington, KY, 40536, USA. linda.vaneldik@uky.edu.; Department of Neuroscience, University of Kentucky, Lexington, KY, 40536, USA. linda.vaneldik@uky.edu.; Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, KY, 40536, USA. linda.vaneldik@uky.edu.
Source: GeroScience [Geroscience] 2019 Oct; Vol. 41 (5), pp. 671-679. Date of Electronic Publication: 2019 May 19.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101686284 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2509-2723 (Electronic) Linking ISSN: 25092723 NLM ISO Abbreviation: Geroscience Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Genetic knockout of myosin light chain kinase (MLCK210) prevents cerebral microhemorrhages and attenuates neuroinflammation in a mouse model of vascular cognitive impairment and dementia.
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  Data: <searchLink fieldCode="AU" term="%22Braun+DJ%22">Braun DJ</searchLink>; Sanders-Brown Center on Aging, University of Kentucky, 101 Sanders-Brown Bldg., 800 S. Limestone Street, Lexington, KY, 40536, USA.<br /><searchLink fieldCode="AU" term="%22Bachstetter+AD%22">Bachstetter AD</searchLink>; Sanders-Brown Center on Aging, University of Kentucky, 101 Sanders-Brown Bldg., 800 S. Limestone Street, Lexington, KY, 40536, USA.; Department of Neuroscience, University of Kentucky, Lexington, KY, 40536, USA.; Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, KY, 40536, USA.<br /><searchLink fieldCode="AU" term="%22Sudduth+TL%22">Sudduth TL</searchLink>; Sanders-Brown Center on Aging, University of Kentucky, 101 Sanders-Brown Bldg., 800 S. Limestone Street, Lexington, KY, 40536, USA.; Department of Physiology, University of Kentucky, Lexington, KY, 40536, USA.<br /><searchLink fieldCode="AU" term="%22Wilcock+DM%22">Wilcock DM</searchLink>; Sanders-Brown Center on Aging, University of Kentucky, 101 Sanders-Brown Bldg., 800 S. Limestone Street, Lexington, KY, 40536, USA.; Department of Physiology, University of Kentucky, Lexington, KY, 40536, USA.<br /><searchLink fieldCode="AU" term="%22Watterson+DM%22">Watterson DM</searchLink>; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.<br /><searchLink fieldCode="AU" term="%22Van+Eldik+LJ%22">Van Eldik LJ</searchLink>; Sanders-Brown Center on Aging, University of Kentucky, 101 Sanders-Brown Bldg., 800 S. Limestone Street, Lexington, KY, 40536, USA. linda.vaneldik@uky.edu.; Department of Neuroscience, University of Kentucky, Lexington, KY, 40536, USA. linda.vaneldik@uky.edu.; Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, KY, 40536, USA. linda.vaneldik@uky.edu.
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  Data: <searchLink fieldCode="JN" term="%22101686284%22">GeroScience</searchLink> [Geroscience] 2019 Oct; Vol. 41 (5), pp. 671-679. <i>Date of Electronic Publication: </i>2019 May 19.
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  Data: Journal Article; Research Support, N.I.H., Extramural
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+International+Publishing%22">Springer International Publishing </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101686284 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2509-2723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225092723%22">25092723 </searchLink><i>NLM ISO Abbreviation: </i>Geroscience <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s11357-019-00072-4
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        Text: English
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      – TitleFull: Genetic knockout of myosin light chain kinase (MLCK210) prevents cerebral microhemorrhages and attenuates neuroinflammation in a mouse model of vascular cognitive impairment and dementia.
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              Text: 2019 Oct
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